摘要
目的 分析糖尿病并发代谢综合征(metabolic syndrome, MS)的临床特征分析,为临床早期预防及早期诊断提供帮助。方法 采用分层整群随机抽样方法抽取2020年1月-2022年12月莆田学院附属医院958例糖尿病患者进行问卷调查、体格检查和实验室检查,根据2005年国际糖尿病联合会代谢综合征诊断标准将人群分为MS组(114例)和非MS组(844例),对两组一般资料、糖代谢和胰岛β细胞功能进行比较,从而得出糖尿病并发代谢综合征的临床特征。结果 MS组的年龄、腰围、体质指数、收缩压、舒张压、三酰甘油均高于非MS人群,高密度脂蛋白固醇低于非MS人群,差异有统计学意义(P<0.05)。MS组的空腹血糖、餐后血糖(0.5 h)、餐后血糖(2 h)、糖化血红蛋白、胰岛素、抵抗指数、β细胞功能指数均高于非MS组,而LnDI1、LnDI2低于非MS组,差异有统计学意义(P<0.05)。结论 相较于单纯糖尿病人群,糖尿病合并MS的人群年龄较大,体质指数、腰围较高,血压、血脂、血糖水平的异常程度也更高,故对于糖尿病患者,定期监测血压、血脂、血糖水平具有重要意义,为临床早期预防及早期诊断提供帮助。
Objective To analyze the clinical characteristics of diabetes complicated with metabolic syndrome,and to provide help for early clinical prevention and diagnosis.Methods 958 patients with diabetes in the affiliated hospital of Putian University from January 2020 to December 2022 were selected by stratified cluster random sampling method for questionnaire survey,physical examination and laboratory examination.According to the diagnostic crite-ria of IDF metabolic syndrome in 2005,the population was divided into MS group(114 cases)and non MS group(844 cases).The general information,glucose metabolism and islet cell function of the two groups were compared,so as to obtain the clinical characteristics of diabetes complicated with metabolic syndrome.Results The age,waist circumfer-ence,BMI,SBP,DBP,and TG of the MS group were higher than those of the non MS population,while HDL-C was lower than that of the non MS population,the difference was statistically significant(P<0.05).The FPG,PG(0.5 h),PG(2 h),HbA1c,LnHOMA-IR,and LnHOMA-βin MS Group were higher than those in the non MS group,while LnDI1 and LnDI2 were lower than those in the non MS group,the difference was statistically significant(P<0.05).Conclusion Compared with people with simple diabetes,people with diabetes combined with MS were older,had higher BMI and waist circumference,and had higher abnormal levels of blood pressure,blood lipids and blood glu-cose.Therefore,for diabetic patients,regular monitoring of blood pressure,blood lipids,blood glucose levels is of great significance for early clinical prevention and early diagnosis.
作者
林梅芳
黄明焕
薛秉玮
LIN Meifang;HUANG Minghuan;XUE Bingwei(Department of Blood Purification Room,Putian University Affiliated Hospital,Putian,Fujian Province,351100 China;Department of Nephrology,Putian University Affiliated Hospital,Putian,Fujian Province,351100 China)
出处
《糖尿病新世界》
2023年第17期39-41,53,共4页
Diabetes New World Magazine
关键词
代谢综合征
糖代谢
血压
血脂
血糖
胰岛Β细胞功能
Metabolic syndrome
Glucose metabolism
Blood Pressure
Blood lipid
Blood glucose
Islet cell function
