摘要
胃癌和肌肉减少症(肌少症)均是与年龄高度相关的疾病。近年来,随着世界人口老龄化的加速,肌少症和胃癌的患病率均持续走高。胃癌患者由于营养成分摄入的减少,导致其肌少症的发生率远远高于其他恶性肿瘤。因此,胃癌患者合并肌少症的现象越来越普遍。由于肌少症人群有着更多的术后并发症、更高的药物不良反应发生率,更高的包括死亡在内的不良结局风险,肌少症被认为是胃癌防治工作最严重的威胁之一。笔者对合并肌少症的胃癌患者从肌少症的诊断、肌少症对胃癌治疗过程的影响和胃癌合并肌少症的治疗方法三个方面进行综合分析,以期指导临床医师进行更好的防治工作。
Gastric cancer and sarcopenia are both highly age-related diseases.In recent years,with the aging acceleration of the world population,the prevalence of sarcopenia and gastric cancer has continued to rise.Theincidence of sarcopenia in patients with gastric cancer is much higher than that of other malignant tumors due tothe reduction of nutrient intake.Therefore,the phenomenon of gastric cancer patients with sarcopenia has becomemore common.Sarcopenia is considered to be one of the most serious threats to the prevention and treatment ofgastric cancer in that people with sarcopenia tend to have more postoperative complications,higher incidence ofadverse drug reactions and higher risk of adverse outcomes including death.This article makes a comprehensiveanalysis of patients with gastric cancer complicated with sarcopenia from three perspectives:the diagnosis ofsarcopenia,the impact of sarcopenia on the treatment of gastric cancer,and the treatment of patients with gastric cancer complicated with sarcopenia,which may guides clinicians to better prevent and treat gastric cancer.
作者
蒋智轩
邵建灿
高泽侃
支怀庆
沈擎正
沈贤
JIANG Zhixuan;SHAO Jiancan;GAO Zekan;ZHI Huaiqing;SHEN Qingzheng;SHEN Xian(Department of Gastrointestinal Surgery,the Second Affiliated Hospital&Yuying Children’s Hospital ofWenzhou Medical University,Wenzhou 325027,China;Department of Gastrointestinal Surgery,the FirstAffiliated Hospital of Wenzhou Medical University,Wenzhou 325015,China)
出处
《温州医科大学学报》
CAS
2023年第11期861-867,共7页
Journal of Wenzhou Medical University
关键词
胃肿瘤
肌少症
营养
诊断
治疗
stomach neoplasms
sarcopenia
nutrition
diagnosis
treatment
