摘要
目的对中药热敷干预腰椎间盘突出症的临床疗效进行系统评价。方法全面检索中国知网(CNKI)、中国生物医学文献数据库(CBM)、万方(Wanfang Data)、维普(VIP)及PubMed、Embase、The Cochrane Library等中、英文数据库从建库至2021年10月30日有关中药热敷干预腰椎间盘突出症(lumbar disc herniation,LDH)的随机对照试验(randomized controlled trials,RCTs),筛选符合要求的文献,采用RevMan 5.3软件进行Meta分析。结果共纳入12项研究,总病患1268例,试验组与对照组各634例。Meta分析结果显示,相较于对照组,中药热敷干预LDH可显著提高总有效率[RR=1.20,95%CI(1.14,1.25),P<0.001]及日本骨科协会(Japanese Orthopaedic Association,JOA)评估治疗分数[MD=2.84,95%CI(2.31,3.38),P<0.001],而疼痛视觉模拟评分法(visual analogue scale,VAS)评分显著低于对照组[MD=-2.26,95%CI(-3.10,-1.43),P<0.001]。结论中药热敷干预LDH可以显著提高患者的临床总有效率,缓解腰腿部疼痛,改善生活质量,缓解心理负担。但由于纳入研究质量偏低,样本数据有限,未来还需纳入更多高质量研究及扩大样本含量,加强临床论证强度。
Objective To conduct a systematic review of the clinical effect of traditional Chinese medicine(TCM)hot compress on patients with lumbar disc herniation(LDH).Methods Clinical randomized controlled trials(RCTs)on TCM hot compress intervention with LDH were searched from CNKI,CBM,Wanfang Data,VIP,PubMed,Embase,The Cochrane Library and other Chinese and English databases from the year of inclusion to October 30,2021 to select the literature meeting the requirements,and Meta-analysis of the efficacy was performed using RevMan 5.3 software.Results Twelve studies with a total of 1268 patients were included,with 634 patients in both of the experimental and control groups.Meta-analysis showed that compared with the control group,treatment of LDH with TCM hot compress in the experimental group can significantly improve the total effective rate in clinical practice[RR=1.20,95%CI(1.14,1.25),P<0.001]and the treatment score of Japanese Orthopaedic Association(JOA)evaluation[MD=2.84,95%CI(2.31,3.38),P<0.001];visual analogue scale(VAS)score was significantly lower than that of the control group[MD=-2.26,95%CI(-3.10,-1.43),P<0.001].Conclusion The intervention of LDH by TCM hot compress can significantly improve the total clinical effective rate,relieve the pain of the waist and leg,further improve the quality of life and relieve the psychological burden of the patients.However,the quality of the included studies is low and the size of the sample data is limited.In the future,it is necessary to improve the quality level of the trial design and sample content,and strengthen the clinical evidence.
作者
杨云云
陈祁青
杨超强
齐鑫
高利娜
蔺海生
元宝华
魏晓涛
Yun-Yun YANG;Qi-Qing CHEN;Chao-Qiang YANG;Xin QI;Li-Na GAO;Hai-Sheng LIN;Bao-Hua YUAN;Xiao-Tao WEI(Graduate School,Gansu University of Chinese Medicine,Lanzhou 730030,China;Bone Injury Institute,Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China)
出处
《数理医药学杂志》
CAS
2023年第11期838-846,共9页
Journal of Mathematical Medicine
基金
甘肃省自然科学基金项目(23JRRA1233)。
关键词
中药热敷
腰椎间盘突出症
随机对照试验
系统评价
META分析
Traditional Chinese medicine hot compress
Lumbar disc herniation
Randomized controlled trial
Systematic review
Meta-analysis
