摘要
目的:观察温针灸配合局部刺络放血治疗类风湿性关节炎(rheumatoid arthritis,RA)的临床疗效。方法:选取2020年3月至2022年3月济源市中医院收治的RA患者84例,按照随机数字表法分为对照组与研究组,每组各42例。对照组给予美洛昔康片口服联合温针灸治疗,研究组在对照组治疗的基础上加用刺络放血治疗。观察两组治疗后实验室指标[血清抗环瓜氨酸肽(cyclic citrulline peptide,CCP)抗体、类风湿因子(rheumatoid factor,RF)、超敏C反应蛋白(hs-C reactive protein,hs-CRP)、T淋巴细胞亚群(CD3^(+)、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))]、临床症状、中医证候积分变化情况及中医证候疗效。结果:研究组治疗后血清抗CCP抗体、RF、hs-CRP水平均低于对照组,差异有统计学意义(P<0.05);研究组治疗后CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)高于对照组,CD8^(+)低于对照组,差异有统计学意义(P<0.05);研究组治疗后关节压痛点数量、关节肿胀数量、晨僵时间及关节疼痛视觉模拟评分均低于对照组,差异有统计学意义(P<0.05);研究组治疗后关节疼痛、晨僵、关节肿胀、肢体酸重、倦怠无力积分和总积分均低于对照组,差异有统计学意义(P<0.05);对照组有效率为76.19%,研究组有效率为92.86%,研究组有效率高于对照组,差异有统计学意义(P<0.05)。结论:温针灸配合局部刺络放血治疗RA,可改善患者临床症状,降低血清抗-CCP抗体、RF、hs-CRP水平,提高机体免疫力。
Objective:To observe the clinical efficacy of warming needle moxibustion combined with local collateral puncture and blood-letting on rheumatoid arthritis(RA).Methods:A total of 84 RA patients admitted to Jiyuan Hospital of Traditional Chinese Medicine from March 2020 to March 2022 were selected and divided into the control group and the study group according to the random number table method,with 42 cases in each group.The control group was given oral Meloxicam Tablets combined with warming needle moxibustion treatment,while the study group was given local collateral puncture and bloodletting on the basis of the control group.Then the la-boratory indexes[including cyclic citrulline peptide(CCP)antibodies,rheumatoid factor(RF),hs-C reactiveprotein(hs-CRP),T lymphocyte subsets(CD3^(+),CD4^(+),CD8^(+),CD4^(+)/CD8^(+))],clinical symptoms,TCM syndrome score changes and TCM syndrome effcacy of the two groups after treatment were observed.Results:After treatment,the serum levels of serum anti-CCP antibody,RF and hs-CRP in the study group were lower than those in the control group,and all the differences were statistically significant(P<0.05);The CD3^(+),CD4^(+),and CD4^(+)/CD8^(+) in the study group were higher than those in the control group,while CD8*was lower than that in the control group,and all the differences were statistically significant(P<0.05);The number of joint tenderness points,the number of joint swelling,the morning stiffness time and the visual simulation score of joint pain in the study group were lower than those in the control group,and all the differences were statistically significant(P<0.05);The scores of joint pain,morning stffness,joint swelling,limb acid weight,lethargy and total score of the study group were lower than those of the control group,and all the differences were statistically significant(P<0.05);The effective rate of the control group was 76.19%,while that of the study group was 92.86%.The effective rate of the study group was higher than that of the control group,and the dfferenc
作者
秦洁
QIN Jie(Jiyuan Hospital of Traditional Chinese Medicine,Jiyuan,Henan,China,459000)
出处
《河南中医》
2023年第11期1737-1741,共5页
Henan Traditional Chinese Medicine
基金
河南省自然科学基金项目(202300410254)。
关键词
类风湿性关节炎
温针灸
局部刺络放血
rheumatoid arthritis(RA)
warming needle moxibustion
local collateral puncture and bloodletting
