摘要
运动能增加骨骼肌中组织蛋白酶B、鸢尾素、乳酸及相关酮体的表达,增加肝脏中组织蛋白酶B的表达,这些因子进入外周血液后通过血脑屏障到达阿尔兹海默症患者大脑,引起海马等脑区BDNF表达升高,促进成年海马神经发生以及改善阿尔兹海默症患者的认知功能.运动可能会降低犬尿氨酸的水平,从而保护阿尔兹海默症患者的大脑.
Exercise increases cathepsin B in the skeletal muscle,iris,lactic acid and the expression of related ketone body,increase the expression of cathepsin B in the liver,these factors enter the peripheral blood through the blood brain barrier arrived in patients with alzheimer's disease,brain caused higher brain areas such as hippocampus BDNF expression,promoting adult hippocampal neurogenesis and improve cognitive function in patients with alzheimer's disease.Similarly,exercise may reduce canine urine levels,thereby protecting the brains of Alzheimer's patients.
作者
张业廷
ZHANG Yeting(Civil Aviation Flight University of China,Sport Department,Guanghan 618307,China)
出处
《牡丹江师范学院学报（自然科学版）》
2023年第4期48-53,共6页
Journal of Mudanjiang Normal University：Natural Sciences Edition
基金
四川省科技计划项目(2020YFH0184)。
关键词
运动
阿尔兹海默症
外周机制
肌肉因子
exercise
Alzheimer's disease
peripheral mechanism
myokines
