摘要
上转换材料因其具有在不同光谱区域之间转换光的能力和特殊的光物理特性,克服了传统荧光材料的一些缺点,为高灵敏度的化学和生物传感器的构建提供了新思路,在分析检测领域引起了广泛关注。本文介绍了近年来利用上转换材料所构建的传感器,其中包含荧光共振能量转移型、辐射能量转移型和非能量转移型三类传感器及其应用于药物和生物活性分子分析测定的相关研究。同时,本文还对此类传感器的未来发展趋势进行了展望,其中上转换材料的制备尺寸以及传感器多功能设计的合理性及其生物稳定性是此类传感器未来发展的重要影响因素。
Upconversion materials have the ability to convert light between different spectral regions and special photophysical properties,and these features overcome some of the disadvantages reported for conventional fluorescent materials and provide opportunities for chemo-and bio-sensing with high sensitivity.And they have attracted wide attention in the field of analysis and detection.Here,we review recent studies on upconversion materials as sensors for the determination of drugs and biomolecules,including fluorescence resonance energy transfer sensors,radiation energy transfer sensors and non-energy transfer sensors.In addition,the future development trends and suggestions of upconversion materials based sensors are given.It is pointed out that the size of upconversion materials,the rationality of multifunctional design and the biological stability of sensors are one of the key development directions in the future.
作者
关桦楠
李明
邢珂
刘晓飞
GUAN Huanan;LI Ming;Xing Ke;LIU Xiaofei(College of Food Engineering,Harbin University of Commerce,Harbin 150028)
出处
《分析科学学报》
CAS
CSCD
北大核心
2023年第5期604-611,共8页
Journal of Analytical Science
基金
国家自然科学基金(31201376)
国家级职业教育教师教学创新团队课题研究项目(ZH2021080101)
黑龙江省自然科学基金(LH2022C046和LH2021B015)
黑龙江省博士后科研启动项目(LBH-Q19027)
黑龙江省领军人才支持计划(2020376)
中央财政支持地方高校发展专项基金(YSL036)
哈尔滨商业大学“青年创新人才”支持计划(2019CX05,2019CX18)。
关键词
上转换发光
上转换纳米粒子
荧光共振能量转移
荧光传感器
分析检测
Upconversion luminescence
Upconversion nanoparticles
Fluorescence resonance energy transfer
Fluorescence sensor
Analysis and determination
