摘要
催化剂负载化是实现绿色催化的有效策略之一。磁性纳米颗粒(MNPs)负载的钯催化剂因其在反应体系中具有良好的分散性、高效的催化活性以及在外加磁场的作用下快速分离、高效回收等特点而被广泛研究并应用于有机合成反应中。其中MNPs负载的多齿钯化合物催化剂(MNPs@L-Pd)相比MNPs负载的钯纳米颗粒催化剂(MNPs@PdNP)具有更好的催化活性和稳定性。这主要是因为MNPs@L-Pd中修饰配体的引入一方面可以调节催化剂金属中心的电子效应和空间位阻实现对其活性的调控,另一方面使得催化剂金属中心与磁性材料之间产生稳定的化学键合的作用以实现对催化剂稳定性的调节。本文主要聚焦于MNPs@L-Pd,从催化剂稳定性和活性出发,分别阐述近10年基于不同配体及配位方式设计合成的MNPs@L-Pd的制备及其在C-X(Cl、Br、I)活化反应中应用的研究进展,并对这些反应进行总结,同时对发展前景作出展望。
Catalyst loading is one of the effective strategies for green catalysis.Palladium(Pd)catalysts supported by magnetic nanoparticles(MNPs)have been widely studied and used in organic synthesis due to their good dispersibility,high catalytic activity,rapid separation under the action of an external magnetic field,and efficient recovery.The MNPs-supported polydentate Pd compound catalyst(MNPs@L-Pd)shows better catalytic activity and stability than the MNPs-supported Pd nanoparticle catalyst(MNPs@PdNP).This is mainly because the introduction of the modified ligand in MNPs@L-Pd can regulate the electronic effect and steric hindrance of the catalyst metal center to achieve the regulation of its activity,on the other hand,it makes the stable chemical bond between the catalyst metal center and the magnetic material to achieve the regulation of stability.This paper mainly focuses on MNPs@L-Pd,the preparation of MNPs@L-Pd based on different ligands and coordination methods and its application in C-X(Cl,Br,I)activation reaction in the past 10 years are reviewed from the aspects of catalyst stability and activity,and the prospect of these reactions are also presented.
作者
马云华
邵晗
蔺腾龙
邓钦月
Yunhua Ma;Han Shao;Tenglong Lin;Qinyue Deng(College of Materials and Chemistry,University of Shanghai for Science and Technology,Shanghai,200093,China)
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2023年第9期1369-1388,共20页
Progress in Chemistry
基金
上海市青年教师培养资助项目(No.slg20035)
关键词
磁性纳米颗粒
钯配合物
负载型催化剂
有机合成反应
magnetic nanoparticle
palladium complex
supported catalyst
organic synthesis reaction
