摘要
心脑血管病是病残和病死的主要原因,动脉粥样硬化是其重要病因。绝经前女性动脉粥样硬化发生率明显低于同龄男性,而绝经后女性动脉粥样硬化发生率显著升高甚至超过同龄男性,与雌激素水平密切相关。本文从影像学检查、危险因素、肠道微生物群和血管炎症反应对动脉粥样硬化影响等方面综述动脉粥样硬化的性别差异,为动脉粥样硬化的精准医疗提供依据。
Cardiovascular and cerebrovascular diseases are the main causes of disability and death,and atherosclerosis is an important cause.The incidence of atherosclerosis in premenopausal women is significantly lower than that in men of the same age,while the incidence of atherosclerosis in postmenopausal women is significantly higher than that in men of the same age,which is closely related to estrogen levels.In this paper,sex differences in atherosclerosis were reviewed from the aspects of imaging examination,risk factors,intestinal microbiome and vascular inflammatory effects on atherosclerosis,to provide evidence for precision medical treatment of atherosclerosis.
作者
王亚伟
田锋
WANG Ya‑wei;TIAN Feng(School of Clinical Medicine,Ji'ning Medical University,Ji'ning 272067,Shandong,China;Department of Neurology,Ji'ning No.1 People's Hospital,Ji'ning 272011,Shandong,China)
出处
《中国现代神经疾病杂志》
CAS
北大核心
2023年第9期864-871,共8页
Chinese Journal of Contemporary Neurology and Neurosurgery
基金
山东省医药卫生科技发展计划(项目编号:202103070424)。
关键词
动脉粥样硬化
性别因素
磁共振成像
危险因素
胃肠道微生物组
炎症
综述
Atherosclerosis
Sex factors
Magnetic resonance imaging
Risk factors
Gastrointestinal microbiome
Inflammation
Review
