摘要
目的:系统描述分析中医技术干预围绝经期失眠的有效性,为临床提供一定参考.方法:计算机检索PubMed、Web of science、Cochrane Library、中国生物医学数据库、中国知网、万方、维普等数据库,检索时限为2003年1月日至2022年12月31日;纳入有关中医技术干预围绝经期失眠的随机对照试验,采用RevMan5.3软件统计分析.结果:共纳入文献21篇,1809例患者.Meta分析结果显示:中医技术干预围绝经期失眠,实验组与对照组在临床疗效(OR=4.01,95%CI:2.89~5.57,P<0.05)、匹兹堡睡眠质量(MD=-2.52,95%CI:-3.29~-1.75,P<0.05)、焦虑(SMD=-0.69,95%CI:-0.90~-0.48,P<0.05)、抑郁(MD=-6.56,95%CI:-8.10~-5.02,P<0.05)方面效果显著,差异具有统计学意义;在性激素水平E2(MD=2.21,95%CI:-1.62~6.03,P>0.05)、性激素水平FSH(MD=0.20,95%CI=-0.43~0.03,P>0.05)方面无统计学差异.结论:中医技术可提高围绝经期失眠患者的睡眠质量,对围绝经期失眠女性的焦虑、抑郁情绪也有一定的改善作用,且中医技术安全性高,值得临床推广.
Objective To systematically describe and analyze the effectiveness of traditional Chinese medicine technique in the intervention of perimenopausal insomnia,and to provide some reference for clinical practice.Methods The databases of PubMed,Web of science,Cochrane Library,China Biomedical Database,CNKI,Wanfang and VIP were searched by computer from January 2003 to December 31,2022.Randomized controlled trials on the intervention of TCM techniques in perimenopausal insomnia were included,and statistical analysis was performed using RevMan5.3 sofiware.Results A total of 21 articles were included,involving 1809 patients.The results of meta-analysis showed that the clinical efficacy of Chinese medicine intervention in perimenopausal insomnia in the experimental group and the control group was significantly improved(OR=4.01,95%CI:2.89-5.57,P<0.05),and Pttsburgh sleep quality(MD=-2.52,95%CI:There were significant effects in-3.29~-1.75,P<0.05),anxiety(SMD=-0.69,95%CI:-0.90~-0.48,P<0.05),depression(MD=-6.56,95%CI:-8.10~-5.02,P<0.05).There were no significant differences in E2(MD=2.21,95%CI:-1.62~6.03,P>0.05)and FSH(MD=0.20,95%CI=-0.43~0.03,P>0.05).Conclusion Chinese medicine technology can improve the sleep quality of perimenopausal insomnia patients,and also has a certain effect on the anxiety and depression of perimenopausal insomnia women,and Chinese medicine technology is safe,worthy of clinical promotion.
作者
文倩倩
邢亚丹
曹牧原
杜彩凤
王丽
赵勇
WEN Qianqian;XING Yadan;CAO Muyuan;DU Caifeng;WANG Li;ZHAO Yong;无(The Second Hospital of Shanxi Medical University,Taiyuan 030001,China;School of Nursing,Shanxi University of Traditional Chinese Medicine,Jinzhong 030619,China;School of Basic Medicine,Shanxi University of Traditional Chinese Medicine,Jinzhong 030619,China;The First Clinical College of Shanxi University of Traditional Chinese Medicine,Jinzhong 030619,China;Department of Neonatology,Shanxi Bethune Hospital,Taiyuan 030032,China)
出处
《湖南师范大学学报（医学版）》
2023年第4期109-115,133,共8页
Journal of Hunan Normal University(Medical Sciences)
基金
山西省自然科学研究面上项目(202103021224297)
山西中医药大学青年科学家培育专题项目(2021PY-QN-02)。
