摘要
目的:探讨加速康复外科理念在肝部分切除术后的镇痛方案的应用效果。方法:回顾性分析2019年1月1日—2021年12月31日我院肝包虫患者中实行肝部分切除术109例患者的临床资料,采用随机对照的方法将患者分为A组和B组,其中A组给予地佐辛注射液镇痛治疗,B组给予氟比洛芬酯联合曲马多注射液镇痛治疗,比较两组术后的疼痛评分、平均住院时间、镇痛药物平均费用、患者满意度及术后并发症和不良反应的发生率。结果:两组术后24 h疼痛评分、术后住院时间、镇痛药物平均费用、患者满意度比较,差异有统计学意义(P<0.05);两组术后48、72 h疼痛评分比较,差异无统计学意义(P>0.05)。A组不良反应发生率、并发症发生率高于B组,差异有统计学意义(P<0.05)。结论:地佐辛注射液与氟比洛芬酯注射液均可以降低术后疼痛,但氟比洛芬酯注射液因不良反应发生率低,经济适用性更强,满意度更高,值得临床使用。
Objective:To explore the application effect of eaccelerated rehabilitation surgery concept in analgesia after partial hepatectomy.Methods:The clinical data of 109 patients with hepatic echinococcosis who underwent partial hepatectomy in our hospital from January 1,2019 to December 31,2021 were retrospectively analyzed.The patients were divided into group A and group B by randomized controlled method.Group A was given dezocine injection for analgesia,and group B was given flurbiprofen axetil combined with tramadol injection for analgesia.The postoperative pain score,average hospitalization time,average cost of analgesic drugs,patient satisfaction and incidence of postoperative complications and adverse reactions were compared between the two groups.Results:There were significant differences in pain score at 24 h after operation,postoperative hospital stay,average cost of analgesic drugs and patient satisfaction between the two groups(P<0.05).There was no significant difference in pain score between the two groups at 48 and 72 h after operation(P>0.05).The incidence of adverse reactions and complications in group A was higher than that in group B,and the difference was statistically significant(P<0.05).Conclusion:Both dezocine injection and flurbiprofen axetil injection can reduce postoperative pain,but flurbiprofen axetil injection is worthy of clinical use because of its low incidence of adverse reactions,stronger economic applicability and higher satisfaction.
作者
陈金凤
塔来提•吐尔干
丁楠
吐尔干艾力·阿吉
蒋铁民
张瑞青
CHEN Jinfeng;TALETTI TULGAN;Ding Nan;TUERGANAILI AJI;JIANG Tiemin;ZHANG Ruiqing(Department of Clinical Pharmacy,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,Xinjiang,China;Department of Hepatobiliary Hydatid Surgery,Digestive Vascular Surgery Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,Xinjiang,China)
出处
《中国药物滥用防治杂志》
CAS
2023年第10期1702-1705,共4页
Chinese Journal of Drug Abuse Prevention and Treatment
基金
国家自然科学基金(项目编号:8196080421)
新疆维吾尔自治区自然科学基金(项目编号:2022D01C219)
新疆维吾尔自治区重点实验室开放课题(项目编号:2021D04024)。
