摘要
目的:讨论分析胃多发白色扁平隆起性病变(multiple whitish flat elevated lesions,MWFLs)患者的临床及病理特点,为日后本病的预防及临床诊治工作提供参考依据。方法:回顾性分析2018—2021年就诊于北京市昌平区中西医结合医院内镜室行胃镜检查的患者临床资料,诊断为MWFLs的患者共计51例,统计分析患者的年龄、性别、幽门螺杆菌(Hp)感染情况及病理特点。结果:两组患者性别间比较,差异有统计学意义(χ^(2)=7.89,P=0.005)。MWFLs患者中合并Hp现症感染的患者3例,感染率约为5.9%。同期行胃镜检查的未合并白色扁平隆起患者Hp现症感染患者1690例,感染率为24.7%,组间比较差异有统计学意义(χ^(2)=9.67,P=0.002)。内镜下观察,51例MWFLs患者发病部位均在胃底穹隆部为主,其中18例MWFLs患者的发病部位还同时存在于胃体。51例患者的病理组织学均提示胃体腺小凹上皮有增生性改变,可见腺管扩张,未见肠上皮化生及炎细胞浸润。结论:MWFLS多见中老年人群,女性发病率高于男性,合并Hp感染率低,病理表现以胃体腺小凹上皮的增生性变化为主。
Objective:The clinical and pathological characteristics of multiple whitish flat elevated lesions(MWFLs)in the stomach are discussed and analyzed in order to provide a reference for the prevention and clinical management of this disease in the future.Methods:The clinical data of patients who underwent gastroscopy in hospitals from 2018-2021 were retrospectively analyzed,and a total of 51 patients were diagnosed with MWFLs.Age,gender,Helicobacter pylori(Hp)infection and pathological characteristics of the patients were statistically analyzed.Results:There were statistically significant differences between the sexes(χ^(2)=7.89,P=0.005).Three of the patients with MWFLs were co-infected with Hp presenting infection,with an infection rate of approximately 5.9%.There were 1690 patients with Hp presenting infection in patients with uncomplicated white flatulence who underwent gastroscopy during the same period,with an infection rate of 24.7%,with statistically significant difference(χ^(2)=9.67,P=0.002).Endoscopically,all 51 patients with MWFLs had a predominantly fundic dome site,and in 18 of them,the site was also present in the gastric body.51 patients had pathological histology suggesting proliferative changes in the epithelium of the glandular hollows of the gastric body,with dilated ducts and no intestinal epithelial hyperplasia or inflammatory cell infiltration.Conclusion:MWFLS is seen in the middle-aged and elderly population,with a higher incidence in women than in men,and a low rate of combined Hp infection,with pathological manifestations dominated by proliferative changes in the epithelium of the gastric body glands.
作者
邢晓丹
朱燃
Xing Xiaodan;ZhuRan(Changping District Hospital of Integrated Traditional Chinese and Western Medicine,Beijing,102208,China)
出处
《黑龙江医学》
2023年第21期2569-2571,共3页
Heilongjiang Medical Journal
关键词
白色扁平隆起性病变
胃镜
临床特点
Multiple whitish flat elevated lesions
Gastroscope
Clinical features
