摘要
Colorectal cancer(CRC)is known to harbor considerable heterogeneity.1 Consequently,it could be hypothesized that similar-appearing tumors might exhibit substantial genetic differences while diverse-appearing tumors may have a similar genetic landscape.2 Due to these differences at the molecular level,they behave or respond differently to therapies as well.CRC progression is a multistep process and involves the accumulation of substantial genetic and epigenetic events in a stage-dependent manner.
基金
funded by the Department of Biotechnology India section order 6242-P103/RGCB/PMD/DBT/SMSV/2015.
