摘要
目的探讨支气管针吸活检术标本不同病理学检查方法对肺癌的诊断价值。方法104例疑似肺癌患者行超声内镜下支气管针吸活检术,取得的标本分别行组织病理学检查、涂片细胞学检查,其中术后病理诊断肺癌77例。以术后病理结果作为“金标准”,比较组织病理学检查、涂片细胞学检查单独及联合检查对肺癌的诊断价值。结果组织病理学检查诊断肺癌74例,确诊率为71.15%;涂片细胞学检查诊断肺癌60例,确诊率为57.69%;两者联合检查诊断肺癌83例,确诊率为79.81%,高于组织病理学检查和涂片细胞学检查。组织病理学检查诊断肺癌的灵敏度、特异度、阳性预测值、阴性预测值、约登指数均高于涂片细胞学检查。两者联合检查诊断肺癌的灵敏度和阴性预测值较高。结论支气管针吸活检术标本进行组织病理学检查能获得更高的诊断效能,必要时可以联合涂片细胞学检查。
Objective To investigate the diagnostic value of different pathological examination methods of bronchial needle aspiration biopsy specimens in lung cancer.Method A total of 104 patients with suspected lung cancer under-went endoscopic ultrasound bronchial needle aspiration biopsy,and the obtained specimens were respectively examined by histopathology and smear cytology,among which 77 cases were pathologically diagnosed as lung cancer.The diagno-sis value of histopathology,smear cytology and combined examination in the lung cancer were compared with the postop-erative pathological results as the gold standard.Result A total of 74 cases were confirmed by histopathology,the diag-nosis rate was 71.15%,60 cases by smear cytology,the diagnosis rate was 57.69%,83 cases by combined examination,the diagnosis rate was 79.81%,which was higher than the histopathlogy and smear cytology.The sensitivity,specificity,positive predictive value,negative predictive value and Youden index of histopathology were higher than those of smear cytology.The combined detection had higher sensitivity and negative predictive value.Conclusion Histopathology can achieve higher diagnostic efficiency under bronchial needle aspiration specimen,and if necessary,it can be combined with smear cytology.
作者
李辉
黄培
庞霞
LI Hui;HUANG Pei;PANG Xia(Department of Pathology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)
出处
《癌症进展》
2023年第17期1901-1902,1933,共3页
Oncology Progress
