摘要
药物性肝损伤是由药物或其代谢产物引起的肝损伤,是最常见的不良反应之一。本文报道1例疑似使用头孢曲松后导致药物性肝损伤的患儿,并结合相关指南及文献,对其进行分析和干预。患儿使用头孢曲松后出现转氨酶异常升高,经过治疗后肝功能逐渐恢复正常。当患儿出现药物性肝损伤时,临床药师应利用自身的专业知识,协助临床医师寻找药物性肝损伤的原因,调整治疗方案,确保临床用药的安全,保障患儿的健康。
Drug-induced liver injury is caused by drugs or their metabolites,which is one of the most common adverse reactions.This article reported one case of suspected drug-induced liver injury in a child after Ceftriaxone,which was analyzed and intervened combined with relevant guidelines and literature.The child showed an abnormal elevation of aminotransferase after Ceftriaxone,and the liver function gradually recovered after treatment.When children have drug-induced liver injury,clinical pharmacists should use their professional knowledge to assist clinicians in finding the cause of drug-induced liver injury and adjust treatment regimen,to ensure the safety of clinical medication and protect the health of children.
作者
李银
孙会静
刘跃琼
古正祥
刘正德
LI Yin;SUN Huijing;LIU Yueqiong;GU Zhengxiang;LIU Zhengde(Department of Pharmacy,Wenshan People’s Hospital,Yunnan Province,Wenshan 663099,China;Department of Pharmacy,People’s Hospital of Guangxi Zhuang Autonomous Region,Guangxi Zhuang Autonomous Region,Nanning 530021,China)
出处
《妇儿健康导刊》
2023年第20期73-75,共3页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
头孢曲松
药物性肝损伤
儿童
Ceftriaxone
Drug-induced liver injury
Children
