摘要
目的探讨1990-2019年江苏省居民缺血性心脏病(ischemic heart disease,IHD)及其危险因素疾病负担变化趋势。方法基于2019年全球疾病负担(global burden of disease,GBD)研究,利用早死损失寿命年(years of life lost,YLL)、伤残损失寿命年(years lived with disability,YLD)、伤残调整寿命年(disability-adjusted of life years,DALY)和人群归因分值(population attributable fraction,PAF)分析1990-2019年江苏省人群IHD疾病负担和归因疾病负担变化趋势,并采用分解法将年龄相关DALY分解为人口增长、年龄构成、年龄别患病率和疾病严重程度4个因素。结果1990-2019年江苏省居民IHD患病数、死亡数和DALY均呈增长趋势;标化YLL率和DALY率呈下降趋势,2010-2019年年均降幅高于1990-2010年。2019年江苏省IHD DALY较1990年增长了75.78%;归因于年龄别患病率、年龄构成、人口增长和疾病严重程度增长率依次为52.06%、46.12%、23.52%和-45.92%。2019年,IHD 26种危险因素归因DALY占IHD总DALY的92.75%;其中环境/职业、行为和代谢危险因素比例分别为38.21%、68.03%和79.07%。2019年IHD归因标化DALY率前5位的危险因素分别为高收缩压、高低密度脂蛋白胆固醇、烟草、室外颗粒物污染和钠摄入过多。近30年间室外颗粒物污染、高BMI、红肉摄入过多、加工肉摄入过多和饮酒5个危险因素年均变化率(annual rate of change,ARC)呈上升趋势,ARC分别为1.29%、1.76%、0.36%、0.32%和4.19%。2010-2019年有10种IHD危险因素的标化DALY率顺位上升,8种危险因素的顺位下降。结论1990-2019年江苏省居民IHD疾病负担总体增加,人口老龄化和年龄别患病率是江苏省IHD DALY增长的主要原因。加强对高血压、高血脂和肥胖的预防和控制,戒烟限酒、减少红肉和加工肉摄入水平,改善室外空气污染是今后江苏省IHD防治的重点。
Objective To examine the trend of burden on ischemic heart disease(IHD)and related risk factors among residents in Jiangsu Province from 1990 to 2019.Methods Based on open access data from the Global Burden of Disease(GBD)2019 Study,years of life lost(YLD),years lived with disability(YLL),disability-adjusted of life years(DALY),and population attributable fraction(PAF)were used to describe the temporal trend burden of IHD and its attributable risk factors from 1990 to 2019.A decomposition method established by Das Gupta P was applied to quantify the burden related to population growth,population age,age-specific prevalence,and the severity of the disease.Results The burden of IHD,in number of prevalence,deaths,and DALYs showed increasing trends from 1990 to 2019.During the same period,age-standardized rates of IHD YLL and DALY showed decreased trends,and the annual decreased rates of change of both YLL and DALY were much higher from 2010 to 2019 than those from 1990 to 2010.The DALY of IHD in 2019 increased by 75.78%compared with 1990,the proportions attributable to age-specific prevalence,population growth,population age and the severity of the disease were 52.06%,46.12%,23.52%,and-45.92,respectively.In 2019,DALY attributable to the 26 modifiable risk factors accounted for 92.75%of the total IHD DALY,and the proportion of environmental/occupational,behavioral and metabolic risk factors was 38.21%,68.03%and 79.07%,respectively.The top five of age-standardized attributable DALY rate in 2019 were high blood pressure,high LDL cholesterol,tobacco,ambient particulate matter pollution,and diet high in sodium.From 1990 to 2019,DALYs attributed to ambient particulate matter pollution(ARC=1.29%),high body-mass index(ARC=1.76%),diet high in red meat(ARC=0.36%),diet high in processed meat(ARC=0.32%),and alcohol use(ARC=4.19%)exhibited the greatest increase.From 2010 to 2019,the age-standardized DALY rate ranking for 10 risk factors for IHD increased,and the age-standardized DALY rate ranking for 8 risk factors decreased.Con
作者
王巍巍
俞浩
洪忻
杨华凤
周海茸
戚圣香
周金意
WANG Weiwei;YU Hao;HONG Xin;YANG Huafeng;ZHOU Hairong;QI Shengxiang;ZHOU Jinyi(Department of Chronic and Non-communicable Disease Control and Prevention,Nanjing Municipal Center for Disease Control and Prevention,Nanjing 210003,China;Department of Chronic and Non-communicable Disease Control and Prevention,Jiangsu Center for Disease Control and Prevention,Nanjing 210009,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2023年第10期1146-1152,共7页
Chinese Journal of Disease Control & Prevention
基金
南京市医学科技发展项目(ZKX21054,ZKX18049)。
关键词
缺血性心脏病
疾病负担
危险因素
变化趋势
Ischemic heart disease
Burden of disease
Risk factors
Variation trend
