摘要
目的探讨全凭静脉麻醉和吸入麻醉对老年患者麻醉效果及术后认知功能的影响。方法选取2020年3月至2021年3月本院收治的88例老年手术患者作为研究对象,按照随机摸球法分为研究组与对照组,每组44例。对照组采用吸入性麻醉,研究组采用全凭静脉麻醉,比较两组各时间段血流动力学指标(心率、收缩压、舒张压)、认知功能恢复程度及术后清醒时间。结果两组心率、舒张压、收缩压组间、时间、交互比较差异有统计学意义(P<0.05)。组内比较:T1、T2、T3时,研究组心率、收缩压均低于T0,T3时收缩压高于T1、T2,舒张压高于T0,差异有统计学意义(P<0.05);T1时,对照组心率、收缩压、舒张压均高于T0,T2时心率、舒张压均高于T0,心率、收缩压均低于T1,T3时心率低于T0、T1、T2,收缩压低于T1、T2,舒张压高于T0,低于T1、T2,差异有统计学意义(P<0.05);其他时间点各指标两两比较差异无统计学意义。组间比较:T0时,两组心率、收缩压、舒张压比较差异无统计学意义;T1、T2、T3时,研究组心率、收缩压、舒张压均低于对照组,差异有统计学意义(P<0.05)。两组美国国立卫生研究院卒中量表NIHSS评分组间、时间、交互比较差异有统计学意义(P<0.05)。组内比较:术后1、3 h,两组NIHSS评分均低于术前、术后6 h,且术后3、6 h,两组NIHSS评分均高于术后1 h,差异有统计学意义(P<0.05);术后6 h,对照组NIHSS评分均低于术前,差异有统计学意义(P<0.05);研究组术前与术后6 h NIHSS评分比较差异无统计学意义。组间比较:术前,两组NIHSS评分比较差异无统计学意义;术后1、3、6 h,研究组NIHSS评分均高于对照组,差异有统计学意义(P<0.05)。研究组术后清醒时间为(17.45±2.45)min,短于对照组的(33.56±3.45)min,差异有统计学意义(P<0.05)。结论与吸入麻醉相比,全凭静脉麻醉安全性更高,更适合老年患者,对血流动力学指标影响较小,术后认知�
Objective To explore the effect of intravenous anesthesia and inhalation anesthesia on anesthetic effect and postoperative cognitive function in elderly patients.Methods A total of 88 elderly surgery patients admitted to our hospital from March 2020 to March 2021 were selected as research subjects,and they were divided into the study group and the control group according to random ball-touching method,with 44 cases in each group.The control group was treated with inhalation anesthesia,and the study group was treated with total intravenous anesthesia,the hemodynamic indexes(heart rate,systolic blood pressure,diastolic blood pressure),cognitive function recovery and postoperative awake time were compared between the two groups.Results There were statistically significant differences in heart rate,diastolic blood pressure,systolic blood pressure between the two groups of group,time points and interaction(P<0.05).Comparison within the group:at T1,T2 and T3,the heart rate and systolic blood pressure were lower than T0,at T3,the systolic blood pressure was higher than T1 and T2,and the diastolic blood pressure was higher than T0,the differences were statistically significant(P<0.05);at T1,the heart rate,systolic blood pressure and diastolic blood pressure of the control group were all higher than T0;at T2,the heart rate and diastolic blood pressure were higher than T0;at T3,the heart rate was lower than T0,T1 and T2,at T3,the systolic blood pressure was lower than T1 and T2,and the diastolic blood pressure was higher than T0 and lower than T1 and T2,the differences were statistically significant(P<0.05);there were no statistically significant differences in each index at other time points.Comparison between groups:at T0,there was no significant difference between the two groups;at T1,T2 and T3,the heart rate,systolic blood pressure and diastolic blood pressure in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).There were significant differences in Na
作者
莫莉平
黄春丽
祝丽艳
MO Liping;HUANG Chunli;ZHU Liyan(Department of Anesthesia,Dengta Central Hospital,Liaoyang,Liaoning,111300,China)
出处
《当代医学》
2023年第14期22-25,共4页
Contemporary Medicine
关键词
全凭静脉麻醉
吸入麻醉
麻醉效果
认知功能
All intravenous anesthesia
Inhalation anesthesia
Anesthetic effect
Cognitive function