摘要
目的探讨经皮椎体成形术对脊柱肿瘤及椎体转移瘤患者VAS评分及效果的影响。方法85例脊柱肿瘤及椎体转移瘤患者,以随机数字表法分组(共两组),观察组行经皮椎体成形术治疗(n=45),对照组行单纯放疗,对比不同治疗方案的疗效。结果治疗有效性评估,观察组高于对照组(P<0.05);观察组患者局部VAS疼痛程度评分值低于对照组(P<0.05);观察组病理性骨折、椎管受累、骨水泥外渗、高钙血症等不良反应总发生率低于对照组(P<0.05);观察组患者ODI椎体功能障碍量表评分低于对照组(P<0.05);观察组患者EORTC肿瘤生存质量调查量表生理、日常生活、认知、情感、社会功能各维度评分值均高于对照组(P<0.05);观察组患者ECOG体力状态量表评分低于对照组(P<0.05)。结论针对脊柱肿瘤及椎体转移瘤患者,经皮穿刺椎体成形术治疗更具治疗有效性,其能够明显减轻患者的疼痛程度,改善患者的椎体功能、生存质量与体力状态,治疗安全性较好,不良反应少,值得推荐、应用。
Objective To investigate the effect of percutaneous vertebroplasty on VAS scores and outcomes in patients with spinal tumors and vertebral metastases.Methods 85 patients with spinal tumors and vertebral metastases were randomly divided into 2 groups using a random number table method.The observation group received percutaneous vertebroplasty(n=45),while the control group received simple radiotherapy.The practical effects of different treatment plans were compared.Results In the evaluation of treatment effectiveness,the observation group was higher than the control group(P<0.05);The local VAS pain score of the observation group patients was lower than that of the control group(P<0.05);The total incidence of adverse reactions such as pathological fractures,vertebral canal involvement,bone cement leakage,and hypercalcemia in the observation group was lower than that in the control group(P<0.05);The ODI vertebral dysfunction scale score of the observation group was lower than that of the control group(P<0.05);The EORTC tumor quality of life survey scale scores of the observation group patients in various dimensions such as physiology,daily life,cognition,emotion,and social function were higher than those of the control group(P<0.05);The ECOG physical state scale score of the observation group patients was lower than that of the control group(P<0.05).Conclusion For patients with spinal tumors and vertebral metastases,percutaneous vertebroplasty is more effective in treatment.It can significantly reduce the pain level of patients,improve their vertebral function,quality of life,and physical condition.The treatment has good safety and fewer adverse reactions,and is worth recommending and applying.
作者
柴旭斌
周英杰
禚汉杰
郝宇鹏
CHAI Xubin;ZHOU Yingjie;ZHUO Hanjie(Henan Luoyang Orthopedic Hospital,Luoyang,471002)
出处
《实用癌症杂志》
2023年第10期1725-1728,共4页
The Practical Journal of Cancer
