摘要
目的探讨口腔病原菌感染及其耐药性检验的临床效果。方法2020年1月—2021年6月,将本院收治的100例口腔感染患者作为本次研究对象,对入选口腔感染患者进行病原菌分布及病原菌抗感染耐药性试验,观察指标:厌氧菌与需氧菌对比情况、厌氧菌情况及耐药性试验结果。结果100例口腔感染患者经病原菌培养后结果显示,共有220株菌株数,其中厌氧菌及需氧菌分别有150株(68.18%)、70株(31.82%),统计学对比差异显著(P<0.05)。厌氧菌共150株,其中口腔链球菌占比最高为59.33%,占比超过所有厌氧菌菌株数的一半;其次为牙龈卟啉单胞菌(9.33%)、中间普氏菌(6.67%)、黑色素普氏菌(6.67%)。厌氧菌耐药性试验,结果显示:此类菌种对红霉素(70.00%)、磺胺甲恶唑(65.33%)及克林霉素(53.33%)有较高的耐药性,对四环素(98.67%)、头孢曲松(93.33%)、万古霉素(98%)有较高的敏感性。结论口腔病原菌感染中以链球菌厌氧菌占比最高,该病症患者对红霉素、磺胺甲恶唑及克林霉素有较高的耐药性,不建议推荐使用;四环素、头孢曲松、万古霉素治疗此病有较高的敏感性,可作为临床首选抗生素用药类型。
Objective To explore the clinical efficacy of oral pathogen infection and drug resistance testing.Methods From January 2020 to June 2021,100 patients with oral infections admitted to our hospital were se-lected as the subjects of this study.Pathogen distribution and antibiotic resistance tests were conducted on selected oral infection patients.Observation indicators:comparison of anaerobic and aerobic bacteria,anaerobic bacteria situation,and drug resistance test results.Results After culturing with pathogenic bacteria,the results of 100 oral infection patients showed a total of 220 bacterial strains,including 150 strains(68.18%)of anaerobic bacteria and 70 strains(31.82%)of aerobic bacteria,with significant statistical differences(P<0.05).There are a total of 150 anaerobic bacteria,among which oral streptococcus accounts for the highest proportion of 59.33%,accounting for more than half of all anaerobic bacteria,followed by Porphyromonas gingivalis(9.33%),Proctella intermedia(6.67%),and Proctella melanin(6.67%).A total of 150 strains of anaerobic bacteria were tested for drug resis-tance.The results showed that these strains were highly resistant to Erythromycin(70.00%),Sulfamethoxazole(65.33%)and Clindamycin(53.33%).These strains are highly sensitive to tetracycline(98.67%),Ceftriaxone(93.33%)and Vancomycin(98.00%).Conclusion Streptococcal anaerobes account for the highest proportion of oral pathogenic bacteria infection.Patients with this disease have high resistance to Erythromycin,Sulfamethoxazole and Clindamycin,which is not recommended.Tetracycline,Ceftriaxone and Vancomycin are highly sensitive to this disease,and can be used as the first choice of antibiotics in clinical use.
作者
林锐
Lin Rui(Laboratory Department of Stomatological Hospital Affiliated to Fujian Medical University,Fuzhou Fujian 350002)
出处
《口岸卫生控制》
2023年第5期59-62,共4页
Port Health Control
关键词
口腔感染
病原菌
厌氧菌
耐药性
Oral infection
Pathogenic bacteria
Anaerobic bacteria
Resistance
