摘要
颅内动脉粥样硬化性疾病(intracranial atherosclerotic disease, ICAD)所致的缺血性卒中致死致残率显著,复发率高。即使经过规范化治疗后的患者,第一年复发率仍超过20%,并且缺血性卒中复发导致的危害比首发卒中更大。因此预测缺血性卒中复发十分重要。磁共振血管壁成像(magnetic resonance vascular wall imaging, MR-VWI)不仅可以识别ICAD病因,对管腔狭窄及管壁情况进行分析,还能定性定量评估斑块成分,识别与缺血性卒中复发关系密切的易损高危斑块,进而指导临床积极干预,降低复发风险。本综述将从MR-VWI优势及其在病因识别、评估影像学特征与复发关系、评估药物及手术治疗效果等方面进行论述,以提高临床对缺血性卒中复发的关注与认识,减少复发引起的相关不良事件的发生。
Ischemic stroke caused by intracranial atherosclerotic disease(ICAD)has a significant mortality and disability rate,and a high recurrence rate.Even after standardized treatment,the first year recurrence rate of patients still exceeds 20%,and the harm caused by ischemic stroke recurrence is greater than that of the first stroke.Therefore,predicting the recurrence of ischemic stroke is very important.Magnetic resonance vascular wall imaging(MR-VWI)can not only identify the cause of ICAD,analyze luminal stenosis and wall conditions,but also qualitatively and quantitatively evaluate plaque components,identify vulnerable high-risk plaques closely related to the recurrence of ischemic stroke,and guide clinical active intervention to reduce the risk of recurrence.This review will discuss the advantages of MR-VWI imaging and its application in etiology identification,evaluation of imaging features and the relationship with recurrence,evaluation of drug and surgical treatment effects,etc.,in order to increase clinical attention and understanding of ischemic stroke recurrence and reduce the occurrence of related adverse events caused by recurrence.
作者
温馨如
宋建勋
黄腾达
WEN Xinru;SONG Jianxun;HUANG Tengda(Guangdong Medical University,Zhanjiang 524023,China;Room of MR,Shenzhen Baoan People's Hospital,Shenzhen 518100,China;Shenzhen Baoan Clinical Medical College of Guangdong Medical University,Shenzhen 518100,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2023年第10期157-161,176,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
深圳市科技创新计划项目可持续发展专项(编号:KCXFZ202002011010360)。
关键词
缺血性卒中
缺血性卒中复发
磁共振血管壁成像
磁共振成像
斑块
ischemic stroke
ischemic stroke recurrence
magnetic resonance imaging vascular wall imaging
magnetic resonance imaging
plaque