摘要
大麻二酚(Cannabidiol,CBD)为大麻提取物中的一种非成瘾性活性成分,是目前研究最热门的植物源性大麻素之一。内源性大麻素系统(endocannabinoidsystem,ECS)在眼表和视网膜中的研究也已经取得显著进展。CBD可以广泛存在于整个眼球,且其分布和功能具有组织特异性。近年来研究发现CBD具有良好的抗炎、抗损伤、降低眼压及神经保护作用。该文详细介绍了CBD在眼部疾病中的研究进展,以及其对各种眼部疾病的治疗潜力。此外,还讨论了CBD在临床眼科治疗中的应用面临的挑战和未来的发展方向。
Cannabidiol(CBD),a non-addictive active ingredient in cannabis extract,is one of the most popular plant-derived cannabinoids.The study on the endoenuous cannabionoid system(ESC)has made significant progress in the ocular surface and retina.CBD exists extensively in the eyeball,and its distrution and functions of anti-inflammatory,antiinjury,reducing intraocular pressure,and neuroprotective effects have been found.This article introduces the research progress in CBD in eye diseases and the therapeutic potential of cannabidiol for various eye diseases in detailed.Furthermore,the challenges and prospect for the application of CBD in clinical ophthalmology were discussed.
作者
马樱格(综述)
李史序
张咏鑫
叶琳(审校)
MA Yingge;LI Shixu;ZHANG Yongxin;YE Lin(The Second Clinical Medical College,Jinan University,Shenzhen 518001,China;Shenzhen Eye Hospital,Jinan University,Shenzhen Eye Institute,Shenzhen 518000,China)
出处
《眼科学报》
CAS
2023年第7期497-503,共7页
Eye Science
关键词
大麻二酚
眼部疾病
临床应用
cannabidiol
eye disease
clinical application
