摘要
胆石症在妊娠期较常见,是常见产科合并症,其形成与雌孕激素、雌激素受体α(ERα)、G蛋白偶联受体30(GPR30)、维生素D缺乏等有关。妊娠期胆石症的发生,其可在一定程度上威胁母婴健康。以往临床多以保守治疗为主,但疗效欠佳,复发率高。近年来,随着医疗技术发展,妊娠不再是手术禁忌证,证实手术治疗妊娠期胆石症较保守治疗效果好,产科并发症发生率降低,其相关研究愈发增多,但其手术治疗时机仍未达成共识,仍需高质量随机对照研究进行临床研究。鉴于此,笔者总结近年来相关学者的相关研究,对妊娠期胆石症发生危险因素及治疗研究新进展进行综述。
Cholelithiasis is common in pregnancy,and it is a common obstetric complication,and its formation is related to estrogen progestogen and estrogen receptorα(ERα),G protein-coupled receptor 30(GPR30),vitamin D deficiency,etc.The occurrence of cholelithiasis during pregnancy may threaten the health of mothers and infants to a certain extent.In the past,conservative management was the main clinical treatment,but the efficacy was poor and the recurrence rate was high.In recent years,with the development of medical technology,pregnancy is no longer a surgical contraindication,it is confirmed that surgical treatment of cholelithiasis during pregnancy is better than conservative management,and the incidence of obstetric complications is reduced,the related research is increasing,however,the timing of surgical treatment has not yet reached consensus,and high-quality randomized controlled research is still needed for clinical research.In view of this,the author summarized the relevant research of relevant scholars in recent years,and reviewed the new progress of research on the risk factors and treatment of cholelithiasis during pregnancy.
作者
蒋粹萃
夏卫红
韩学义
吴星萍
黄嫱
陈晓梅
JIANG Cuicui;XIA Weihong;HAN Xueyi;WU Xingping;HUANG Qiang;CHEN Xiaomei(Fangchenggang Hospital of Traditional Chinese Medicine,Fangchenggang 538021,China;不详)
出处
《中外医学研究》
2023年第27期176-179,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
妊娠期胆石症
危险因素
治疗研究
新进展
Cholelithiasis during pregnancy
Risk factors
Treatment research
New progress
