摘要
目的:分析颈内动脉系统短暂性脑缺血发作(transient ischemic attack,TIA)后再发脑卒中的相关影响因素。方法:回顾性分析2018年1月—2020年6月收治于厦门大学附属第一医院的79例颈内动脉系统TIA患者的资料,并根据是否再发脑卒中分为无脑卒中组(n=48)和脑卒中组(n=31)。对比两组患者的一般资料、临床资料及颈动脉内膜中层厚度(carotid intima-media thickness,CIMT),采用多因素logistic回归模型对颈内动脉系统TIA患者再发脑卒中的影响因素进行分析。结果:脑卒中组高血压、既往脑梗死病史比例高于无脑卒中组,差异有统计学意义(P<0.05);两组其余一般资料对比,差异无统计学意义(P>0.05)。脑卒中组首次发作距就诊时间、症状持续时间长于无脑卒中组,CIMT大于无脑卒中组,差异有统计学意义(P<0.05);两组甘油三酯(triacylglycerols,TG)、低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)、总胆固醇(total cholesterol,TC)及高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)对比,差异无统计学意义(P>0.05)。多因素logistic回归分析结果显示,既往脑梗死病史、首次发作距就诊时间、症状持续时间及CIMT是颈内动脉系统TIA后再发脑卒中的危险因素(P<0.05)。结论:颈内动脉系统TIA后再发脑卒中的风险较高,既往脑梗死病史、首次发作距就诊时间、症状持续时间及CIMT是颈内动脉系统TIA后再发脑卒中的影响因素,同时还需注意高血压在风险评估时的重要性。
Objective:To analyze the related influence factors of recurrent stroke after transient ischemic attack(TIA)of internal carotid artery system.Method:The clinical data of 79 patients with TIA of internal carotid artery system admitted to the First Affiliated Hospital of Xiamen University from January 2018 to June 2020 were retrospectively analyzed.The patients were divided into non-stroke group(n=48)and stroke group(n=31)according to whether they developed into recurrent stroke.The general data,clinical data,and carotid intima-media thickness(CIMT)of patients between the two groups were compared,and the multivariate logistic regression model was used to analyze the influencing factors of recurrent stroke in patients with TIA of internal carotid artery system.Result:The proportions of hypertension and history of previous cerebral infarction in stroke group were higher than those in non-stroke group,the differences were statistically significant(P<0.05).There were no significant differences in other general data between the two groups(P>0.05).In the stroke group,the time from first attack to treatment and the duration of symptoms were longer than those in the non-stroke group,and the CIMT was thicker than that in the non-stroke group,the differences were statistically significant(P<0.05).There were no significant differences in triacylglycerols(TG),low-density lipoprotein cholesterol(LDL-C),total cholesterol(TC)and high-density lipoprotein cholesterol(HDL-C)between the two groups(P>0.05).The results of multivariate logistic regression analysis showed that the history of previous cerebral infarction,the time from first attack to the treatment,the duration of symptoms and CIMT were the influencing factors of previous recurrent stroke after TIA(P<0.05).Conclusion:The risk of recurrent stroke after TIA in the internal carotid artery system is higher.The history of previous cerebral infarction,the time from first attack to treatment,the duration of symptoms and CIMT are the influence factors of recurrent stroke after TIA
作者
黄上萌
黄俊卿
万慧娟
兰文斌
陈津瀚
HUANG Shangmeng;HUANG Junqing;WAN Huijuan;LAN Wenbin;CHEN Jinhan(The First Affiliated Hospital of Xiamen University,Xiamen 361003,China;不详)
出处
《中外医学研究》
2023年第26期157-160,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
厦门大学附属第一医院2020年度转化医学研究孵育基金资助项目(XFY2020003)。
