摘要
目的:探讨联合检测血清降钙素原(PCT)、C反应蛋白(CRP)、中性粒细胞百分比(NEUT%)对糖尿病足(DF)患者发生感染的预测价值。方法:选取2020年3月—2022年10月漳州市长泰区医院收治的93例DF患者,依据临床体征、足溃疡组织分泌物细菌培养结果等评估患者发生感染情况,并分为感染组、未感染组;检测并比较两组血清PCT、CRP、NEUT%水平,绘制受试者工作特征曲线(ROC曲线)分析血清PCT、CRP、NEUT%单独及联合检测对DF患者发生感染的预测价值。结果:93例DF患者中,有34例发生感染,感染率为36.56%。感染组血清PCT、CRP、NEUT%水平均较未感染组高,差异有统计学意义(P<0.05)。绘制ROC曲线发现,血清PCT、CRP、NEUT%单独及联合检测预测DF患者发生感染的AUC分别为0.789、0.742、0.725、0.927,有一定的预测价值,且联合检测价值最高。结论:联合检测血清PCT、CRP、NEUT%对DF患者发生感染的预测风险较高,可将三者作为评价DF患者发生感染风险的重要辅助指标。
Objective:To investigate the predictive value on serum procalcitonin(PCT),C-reactive protein(CRP)and neutrophil percentage(NEUT%)in patients with diabetic foot(DF).Method:A total of 93 DF patients admitted to the Zhangzhou Changtai District Hospital from March 2020 to October 2022 were selected.According to clinical signs and bacterial culture results of foot ulcer tissue,the infection situation of the patients was assessed and divided into infected group and uninfected group.The serum levels of PCT,CRP and NEUT%were detected and compared between the two groups,and the receiver operating characteristic curve(ROC curve)was drawn to analyze the predictive value of serum PCT,CRP and NEUT%alone and combined for infection in patients with DF.Result:Among the 93 DF patients,34 patients were infected,the infection rate was 36.56%.The levels of serum PCT,CRP and NEUT%in infected group were higher than those in uninfected group,and the differences were statistically significant(P<0.05).ROC curve showed that the AUC values of serum PCT,CRP and NEUT%alone and in combination of predicting infection in DF patients were 0.789,0.742,0.725,0.927 respectively,which had certain diagnostic value,and combined detection had the highest diagnostic value.Conclusion:The combined detection of serum PCT,CRP and NEUT%has a higher predictive risk of infection in DF patients,which can be used as important auxiliary indicators to evaluate the risk of infection in DF patients in the future.
作者
杨彩娥
YANG Cai’e(Zhangzhou Changtai District Hospital,Zhangzhou 363900,China)
出处
《中外医学研究》
2023年第25期74-77,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
