摘要
目的探讨团队全程化管理联合三七红藤汤对输卵管阻塞致不孕症患者康复效果和妊娠结局的影响。方法选取2020年1—12月在温州市中医院治疗的98例输卵管阻塞引发的不孕症患者为研究对象,采用随机数字表法将患者分为对照组和观察组,每组各49例。对照组患者进行常规治疗,观察组患者进行团队全程化管理联合三七红藤汤治疗。比较治疗后两组患优势卵泡数目、子宫内膜厚度及激素水平,并比较两组患者妊娠结局。结果治疗后,观察组患者优势卵泡数目[(4.12±1.43)个]和子宫内膜厚度[(14.12±2.12)mm]均高于对照组[(2.12±1.13)个、(9.01±1.02)mm],差异均有统计学意义(t=7.681、15.204,均P<0.05)。治疗后,观察组患者雌二醇(E2)、黄体生成素(LH)、孕酮(P)及卵泡刺激素(FSH)水平[(155.17±23.45)pmol/L、(19.71±4.58)IU/L、(14.73±3.27)nmol/L及(6.63±1.64)IU/L]均高于对照组[(120.82±25.17)pmol/L、(17.45±3.46)IU/L、(11.08±2.93)nmol/L及(6.40±1.43)IU/L],差异均有统计学意义(t=8.671、5.460、5.822及0.217,均P<0.05)。治疗后,观察组患者妊娠成功率(85.71%)高于对照组(59.18%),卵泡成熟未妊娠率(8.16%)、卵泡发育失败率(6.12%)均低于对照组(24.49%、16.33%),差异均有统计学意义(χ^(2)=7.076、7.317及6.923,均P<0.05)。结论团队全程化管理联合三七红藤汤治疗输卵管阻塞致不孕症临床效果显著,可促进患者保留优势卵泡,增加子宫内膜厚度,有效改善激素水平,提高患者成功妊娠率,改善妊娠结局,值得临床推广应用。
Objective To investigate the effect of team team-based totalized management combined with Sanqi Hongteng Decoction on the rehabilitation effect and pregnancy outcome of patients with infertility due to tubal obstruction.MethodsNinety-eight patients with in-fertility caused by tubal obstruction treated in Wenzhou Hospital of Traditional Chinese Medicine from January to December 2020 were select-ed as the study subjects,and the patients were divided into the control group and the observation group by using the method of randomized numerical table,with 49 cases in each group.Patients in the control group were treated with conventional treatment,while patients in the ob-servation group were treated with team team-based totalized management combined with Sanqi Hongteng Decoction.The number of dominant follicles,endometrial thickness and hormone levels were compared between the two groups after treatment,and the pregnancy outcomes were also compared between the two groups.Results After treatment,the number of dominant fllicles[(4.12±1.43)and endometrial thickness[(14.12±2.12)mm]in the observation group were higher than that in the control group[(2.12±1.13)and(9.01±1.02)mm],and the differences were statisticaly significant(t=7.681,15.204,all P<0.05).Afer treatment,the levels of estradiol(E2),luteinizing hor-mone(LH),progesterone(P)and fllicle-stimulating hormone(FSH)were higher in the observation group[(155.17±23.45)pmol/L,(19.71±4.58)IU/L,(14.73±3.27)nmol/L,and(6.63±1.64)IU/L]than in the control group[(120.82±25.17)pmol/L,(17.45±3.46)IU/L,(11.08±2.93)nmol/L and(6.01±1.43)IU/L],the differences were statistically significant(t=8.671,5.460,5.822 and 0.217,all P<0.05).After treatment,the pregnancy success rate of patients in the observation group(85.71%)was higher than that of the control group(59.18%),while the follicular maturation and non-pregnancy rate(8.16%)and fllicular development fail-ure rate(4.08%)were lower than that of the control group(24.49%,16.33%),and the differences were all statistically signi
作者
周熹
孙云
ZHOU Xi;SUN Yun(Wenzhou Hospital of Traditional Chinese Medicine,Wenzhou,Zhejiang 325000,China)
出处
《中国妇幼保健》
CAS
2023年第19期3718-3721,共4页
Maternal and Child Health Care of China
基金
浙江省温州市科技计划项目(ZS2017019)。
关键词
团队全程化管理
三七红藤汤
输卵管阻塞致不孕症
康复效用
妊娠结局
Team whole process management
Sanqi Hongteng Decoction
Fallopian tube obstruction caused infertility
Rehabilitation effect
Pregnancy outcomes