摘要
目的观察雷火灸结合饮食疗法治疗癌症患者化疗相关性便秘的临床疗效。方法将2021年9月至2022年9月收治的癌症化疗相关性便秘患者104例按照随机数字表法分为2组,对照组52例予饮食疗法治疗,治疗组52例对照组基础上联合雷火灸治疗。2组均治疗5周后统计疗效,比较2组治疗前后生活质量[采用胃肠道生活质量指数(GIQLI)进行评价]、便秘症状(采用Wexner便秘评分进行评价)及肛门直肠压指标(包括直肠静息压及最大收缩压)水平变化情况,比较2组治疗期间腹胀、焦虑烦躁、腹痛、食欲不振不良反应的发生情况。结果治疗组总有效率94.23%(49/52),对照组总有效率78.85%(41/52),治疗组总有效率高于对照组(P<0.05)。与本组治疗前比较,2组治疗后生活质量GIQLI评分均降低(P<0.05),且治疗组治疗后生活质量GIQLI评分低于对照组(P<0.05)。与本组治疗前比较,2组治疗后便秘症状Wexner便秘评分均降低(P<0.05),且治疗组治疗后便秘症状Wexner便秘评分低于对照组(P<0.05)。与本组治疗前比较,2组治疗后肛门直肠压指标直肠静息压及最大收缩压水平均升高(P<0.05),且治疗组治疗后直肠静息压及最大收缩压水平均高于对照组(P<0.05)。治疗组治疗期间腹胀、烦躁焦虑、腹痛、食欲不振发生率均比对照组低(P<0.05)。结论雷火灸结合饮食疗法治疗癌症患者化疗相关性便秘疗效确切,可有效提高患者生活质量,改善便秘症状,促进排便,减少不良反应的发生。
Objective To investigate the effect of thunder-fire moxibustion(TFM)combined with diet therapy on chemotherapy-related constipation in cancer patients.Methods From September 2021 to September 2022,totally 104 patients with cancer chemotherapy-related constipation were randomized 1∶1 to receive the diet therapy(the control group)or TFM combined with diet therapy(the treatment group).The therapeutic effects of both groups were statistically calculated after 5 weeks of treatment,aiming to compare the gastrointestinal quality of life index(GIQLI)score,the Wexner constipation score,and anorectal pressure indicators including anal canal rest pressure(ACRP),maximum anal systolic pressure(MASP).The treatment-emergent adverse events(TEAEs)such as abdominal distension,anxiety and irritability,abdominal pain,and inappetence were assessed between the two groups.Results The total effective rate in the treatment group was significantly higher than that of the control group(94.23%[49/52]vs 78.85%[41/52],P<0.05).After treatment,the GIQLI scores in the both groups were significantly reduced(P<0.05),and this reduction was more obvious in the treatment group(P<0.05).The Wexner scores of the both groups decreased significantly after treatment(P<0.05),and the decrease was more pronounced in the treatment group than the control group(P<0.05).The levels of ACRP and MASP in the both groups increased significantly after treatment(P<0.05),and which in the treatment group were significantly higher compared with the control group(P<0.05).The incidences of TEADs in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion For cancer patients with chemotherapy-related constipation,the combined application of TFM and diet therapy has definite efficacy.It can effectively improve the patient's quality of life,relieve constipation symptoms,promote defecation,and reduce adverse reactions.
作者
丁颖
席从林
严素华
安李一
徐芳
殷艳
袁娴
DING Ying;XI Conglin;YAN Suhua;AN Liyi;XU Fang;YIN Yan;YUAN Xian(Department of Oncology,Huai'an Second People's Hospital,Huai'an,Jiangsu 223001;Nursing Major,Jiangsu College of Nursing,Huai'an,Jiangsu 223001;Department of Nursing,Huai'an Second People's Hospital,Huai'an,Jiangsu 223001;Department of Gastroenterology,Huai'an Second People's Hospital,Huai'an,Jiangsu 223001;Department of Cardiology,Huai'an Second People's Hospital,Huai'an,Jiangsu 223001)
出处
《河北中医》
2023年第10期1689-1692,共4页
Hebei Journal of Traditional Chinese Medicine
关键词
癌症
化疗
便秘
雷火灸
饮食
Cancer
Chemotherapy
Constipation
Thunder-fire moxibustion
Diet therapy
