摘要
目的:分析声带脂肪注射术对单侧声带麻痹患者的疗效。方法:选取100例单侧声带麻痹患者作为研究对象,按照治疗方法将患者不同分为研究组与对照组,每组各50例。对照组接受常规药物治疗;研究组接受声带脂肪注射术。对比两组患者治疗前、治疗后1、6及12个月后声门裂隙、麻痹侧声带表面积、频率微扰、振幅微扰、标准化声门噪声能量(NNE)、最长声时(MPT)、嗓音障碍指数量表(VHI)评分和嗓音嘶哑评估(GRBAS),记录两组并发症发生情况。结果:治疗后,两组麻痹侧声带面积均较治疗前增加,且研究组治疗后各时间点均高于对照组(P<0.05);声带闭合时声门裂隙均较治疗前缩小(P<0.05),且研究组治疗后各时间点均小于对照组(P<0.05)。治疗后,两组患者MPT均较治疗前延长,且研究组治疗后各时间点均长于对照组;NNE、频率微扰、振幅微扰较治疗前降低(P<0.05),且研究组治疗后各时间点均低于对照组(P<0.05)。治疗后,两组患者功能、生理、情感各维度评分及总分均低于治疗前,且研究组除生理维度治疗后1个月外,其余各维度治疗后各时间点均低于对照组(P<0.05)。治疗后,两组患者G、R、B评分较治疗前降低(P<0.05),且研究组治疗后各时间点均低于对照组(P<0.05)。两组患者并发症发生率比较,差异无统计学意义(P>0.05)。结论:声带脂肪注射术有助于消除单侧声带麻痹患者声门裂隙,提高患者嗓音质量,远期效果较药物治疗稳定,值得推广。
Objective:To analyze the effect of vocal cord fat injection on patients with unilateral vocal cord paralysis.Methods:100 patients with unilateral vocal cord paralysis were selected and divided into study group and control group according to the difference of treatment methods,50 cases in each group.The control group was treated with medication,and the study group was treated with vocal cord fat injection.The glottic fissure,the surface area of the paralytic vocal cord,frequency perturbation,amplitude perturbation,normalized glottic noise energy(NNE),the longest sound time(MPT),voice disorder index(VHI)scores and GRBAS scale before treatment,after 1,6,and 12 m of treatment were compared between the two groups,and the incidence of complications was compared between the two groups.Results:The area of paralytic vocal cords in both groups increased compared to before treatment,and the study group at each time points after treatment was higher than the control group(P<0.05).The glottic fissure was smaller when the vocal cord was closed than that before treatment(P<0.05),and the study group at each time points after treatment was lower than the control group(P<0.05).After treatment,the MPT of patients in both groups was longer than that before treatment,and the NNE,frequency perturbation and amplitude perturbation were lower than those before treatment(P<0.05).Moreover,the MPT of the treatment group at each time point after treatment was longer than that of the control group,and the NNE,frequency perturbation and amplitude perturbation were lower than those of the control group(P<0.05).After treatment,the average scores of function,physiology and emotion as well as the total score in the two groups were lower than those before treatment,and the study group had lower scores in all dimensions at all time points after treatment than the control group,except for the physiological dimension 1 month after treatment(P<0.05).After treatment,the G,R and B scores of patients in the two groups were lower than those before treatmen
作者
卢柳斌
蓝嘉芸
周霓
LU Liu-bin;LAN Jia-yun;ZHOU Ni(Department of Otorhinolaryngology Head and Neck Surgery,Liuzhou Workers'Hospital,Liuzhou 545027,Guangxi,China)
出处
《川北医学院学报》
CAS
2023年第9期1222-1226,共5页
Journal of North Sichuan Medical College
基金
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20211409)。
关键词
声带脂肪注射术
单侧声带麻痹
声门裂隙
麻痹侧声带表面积
嗓音质量
Vocal cord fat injection
Unilateral vocal cord paralysis
Glottic fissure
Surface area of paralytic vocal cord
Voice quality
