摘要
目的探讨CT、磁共振成像(magnetic resonance imaging,MRI)对子宫内膜癌(endometrial carcinoma,EC)中的的诊断价值,同时分析联合检查在子宫内膜癌诊断中的应用价值。方法回顾性选取本院2019年12月至2021年12月期间收治的100例疑似EC的子宫内膜病变患者临床资料,患者均在本院接受CT及MRI扫描检查。以最终病理诊断结果为金标准,分析CT、MRI及联合检测对EC的评估价值。同时采用免疫组织化学法测定患者术后病理切片组织内VEGF表达水平,联合影像学手段判断EC恶性程度。结果经术后病理检查确诊,100例疑似EC的子宫内膜病变患者中有EC患者87例,良性病变13例。根据Kappa一致性检验,CT与病理检测结果一致性较差(Kappa=0.246),MRI与病理检测结果一致性一般(Kappa=0.412),CT联合MRI与病理检测结果一致性较好(Kappa=0.75)。将EC纳入阳性组,良性病变纳入阴性组,CT、MRI、CT联合MRI的诊断灵敏度为67.82%(59/87)、72.41%(63/87)、90.80%(79/87),特异度为76.92%(10/13)、92.31%(12/13)、100.00%(13/13),准确性为69.00%(69/100)、78.00%(78/100)、92.00%(92/100)。CT联合MRI对EC的诊断效能高于单项CT、MRI。结论CT联合MRI对EC的诊断效能较高,且与病理检查结果一致性较好,对临床上早期难以确诊的子宫内膜病变具有较高应用价值。
Objective To investigate the diagnostic value of CT and MAGNETIC resonance imaging(MRI)in endometrial carcinoma(EC),and to analyze the application value of combined examination in endometrial carcinoma.Methods The clinical data of 100 patients with endometrial lesions suspected of EC admitted to our hospital from December 2019 to December 2021 were retrospectively selected.All patients received CT and MRI scans in our hospital.The final pathological diagnosis was taken as the gold standard to analyze the evaluation value of CT,MRI and combined detection for EC.At the same time,the expression level of VEGF in postoperative pathological sections of patients was determined by immunohistochemistry,and the degree of EC malignancy was determined by imaging.Results 87 cases of EC and 13 cases of benign endometrial lesions were confirmed by postoperative pathological examination.According to Kappa consistency test,the consistency between CT and pathological test was poor(Kappa=0.246),the consistency between MRI and pathological test was general(Kappa=0.412),and the consistency between CT combined with MRI and pathological test was good(Kappa=0.75).The diagnostic sensitivity of CT,MRI and CT combined WITH MRI were 67.82%(59/87),72.41%(63/87),90.80%(79/87)when EC was included in the positive group and benign lesions were included in the negative group.The specificity was 76.92%(10/13),92.31%(12/13),100.00%(13/13),and the accuracy was 69.00%(69/100),78.00%(78/100),92.00%(92/100).CT combined with MRI has higher diagnostic efficiency for EC than single CT and MRI.Conclusion CT combined with MRI has a high diagnostic efficiency for EC,and is consistent with the results of pathological examination.It has a high application value for early clinical difficult to diagnose endometrial lesions.
作者
李兆蕾
窦斌
杨斐
盛学莲
姚永杰
Li Zhao-lei;DOU Bin;Yang FEI;SHENG Xue-lian;YAO YONG-jie(Gynecology Department of Rizhao Central Hospital,Rizhao 276800,Shandong Province,China;Image Department of Rizhao Central Hospital,Rizhao 276800,Shandong Province,China)
出处
《中国CT和MRI杂志》
2023年第9期151-153,共3页
Chinese Journal of CT and MRI
关键词
子宫内膜癌
CT
磁共振成像
Endometrial Carcinoma
Computed Tomography(CT)
Magnetic Resonance Imaging
