摘要
目的评价乌贝散合小陷胸汤联合PPI治疗肝胃郁热型非糜烂性反流病的临床疗效。方法选择2019年7月—2022年7月淮安市洪泽区中医院脾胃病科收治的92例肝胃郁热型非糜烂性反流病患者作为研究对象,采用SAS9.2软件进行区组随机分组,治疗组48例,对照组44例。治疗组给予乌贝散合小陷胸汤,同时服用兰索拉唑肠溶片;对照组给予兰索拉唑肠溶片,两组患者均治疗8周。观察两组患者治疗前后中医证候积分、症状积分、Zung焦虑自评量表、Zung抑郁自评量表和SF-36生活质量评分等变化。结果对照组总有效率低于治疗组,差异有统计学意义(P<0.05);治疗后,两组患者中医证候单项积分均下降,治疗组烧心、反酸、胸骨后灼痛及胃脘灼痛这四项积分均低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者SAS、SDS评分和生活质量评分均下降,且治疗组SAS、SDS评分和生活质量评分均低于对照组,差异有统计学意义(P<0.05)。结论乌贝散合小陷胸汤联合PPI治疗肝胃郁热型非糜烂性反流病能够有效改善患者的症状、心理状态和生活质量。
Objective To evaluate the clinical eff ect of Wubei Powder and Xiaoxianxiong Decoction combined with PPI in the treatment of non erosive refl ux disease of liver stomach heat stagnation type.Method A total of 92 patients with non-erosive refl ux disease of liver and stomach depression heat were selected from the spleen and Stomach Disease Department of Hongze District Hospital of Traditional Chinese Medicine,Huai'an City from July 2019 to July 2022.SAS9.2 software was used to randomly divide the patients into 2 groups,48 in the treatment group and 44 in the control group.The treatment group was given Wubei Powder and Xiaoxianxiong Decoction,take Lansoprazole enteric coated tablets at the same time.Lansoprazole enteric coated tablets in the control group.Both groups were treated for 8 weeks.Observe the changes of symptoms,TCM syndrome scores,Zung Self Rating Anxiety Scale,Zung Self Rating Depression Scale and SF-36 quality of life scores of the two groups before and after treatment.Results The total eff ective rate in the treatment group was higher than that in the control group.The clinical effi cacy of the treatment group was signifi cantly better than the control group(P<0.05).After treatment,the single score of TCM syndromes in the two groups decreased signifi cantly,and the four scores of heartburn,acid regurgitation,poststernal burning pain and epigastric burning pain in the treatment group were signifi cantly lower than those in the control group(P<0.05).After treatment,the SAS,SDS scores and quality of life scores of patients in the two groups decreased signifi cantly,and the SAS,SDS scores and quality of life scores in the treatment group were signifi cantly lower than those in the control group(P<0.05).Conclusion Wubei powder combined with Xiaoxianxiong decoction and PPI can eff ectively improve the symptoms,psychological status and quality of life of patients with non erosive refl ux disease of liver stomach heat stagnation type.
作者
付彦俐
秦阳
刘怀磊
FU Yan-li;QIN Yang;LIU Huai-lei(Gastroenterology department,Huai'an Hongze District Hospital of Traditional Chinese Medicine,Huai'an Jiangsu 223199,China)
出处
《中华养生保健》
2023年第20期40-43,共4页
CHINESE HEALTH CARE
关键词
非糜烂性反流病
乌贝散
小陷胸汤
肝胃郁热型
non erosive refl ux disease
wubei powder
xiaoxianxiong decoction
liver and stomach stasis heat type
