摘要
目的分析2018—2022年成都市新都区疑似预防接种异常反应(AEFI)监测情况,为评价疫苗接种的安全性和提高预防接种服务质量提供依据。方法通过四川省免疫规划信息管理系统和AEFI个案监测系统分别收集2018年1月1日至2022年12月31日成都市新都区疫苗接种数据以及报告的AEFI数据,采用卡方检验分析AEFI报告发生率的差异,以P<0.05为差异有统计学意义。结果2018—2022年成都市新都区共报告AEFI 2604例,其中一般反应2398例,占92.09%,异常反应166例,占6.37%。异常反应中以过敏反应为主,占95.78%。AEFI发生主要集中在5至7月,年龄集中在1岁及以下。结论2018—2022年成都市新都区报告的AEFI以一般反应为主,临床表现多为发热、接种部位红肿、硬结,疫苗接种安全性良好。
Objective To analyze the surveillance of suspected adverse event following immunization(AEFI)in Xindu District of Chengdu City from 2018 to 2022,and to provide basis for evaluating the safety of vaccination and improving the quality of vaccination service.Methods The vaccination data and reported AEFI data of Xindu District of Chengdu City from January 1,2018 to December 31,2022 were collected through Sichuan Provincial Immunization Program Information Management System and AEFI Case Surveillance System,respectively.Chi-square test was used to analyze the differences in the reported incidence of AEFI.And P<0.05 was considered statistically significant.Results A total of 2604 AEFI cases were reported in Xindu District of Chengdu City from 2018 to 2022,of which 2398 cases were general reactions,accounting for 92.09%,and 166 cases were abnormal reactions,accounting for 6.37%.Anaphylaxis was the main abnormal reaction,accounting for 95.78%.AEFI occurred mainly in May to July,and the age was concentrated in 1 year and younger.Conclusions The reported AEFI cases in Xindu District of Chengdu City from 2018 to 2022 were mainly general reactions,and the clinical manifestations were mainly fever,redness,swelling and induration at the vaccination site,which indicated good vaccine safety.
作者
凌云
文小华
周福明
周良
LING Yun;WEN Xiaohua;ZHOU Fuming;ZHOU Liang(Xindu Center for Disease Control and Prevention,Chengdu 610500,Sichuan Province,China)
出处
《寄生虫病与感染性疾病》
CAS
2023年第3期176-181,共6页
Parasitoses and Infectious Diseases
关键词
疫苗
疑似预防接种异常反应
监测
vaccine
suspected adverse event following immunization
surveillance
