摘要
目的:了解广州地区门诊患者沙眼衣原体、解脲脲原体、生殖支原体的感染人群及特征,为临床诊疗以及优生优育提供流行病学参考。方法:选取2021年9月-2022年9月来中山大学孙逸仙纪念医院就诊的门诊患者的泌尿生殖道分泌物或尿液标本共计1137份,统计分析患者泌尿生殖道分泌物中CT、UU和MG的RNA检测结果。结果:广州地区门诊患者CT、UU和MG阳性率分别为4.05%(46/1137),31.05%(353/1137),1.50%(17/1137),其中女性患者UU的阳性检出率显著高于男性,差异有统计学意义(χ^(2)=28.676,P<0.001),男性患者中MG的阳性检出率显著高于女性,差异有统计学意义(χ^(2)=6.236,P<0.05),CT阳性检出率性别差异无统计学意义。检测出两种及三种病原体混合感染共有27例,混合感染阳性率为2.37%(27/1137),门诊患者混合感染的类型以CT+UU为主。CT、UU和MG感染人群主要分布在21-40岁,另外≤20岁男性患者人群中,CT、UU和MG均有较高的检出率。结论:门诊患者CT、UU和MG检出率较高,并存在多种病原体混合感染现象,临床在诊治时需要重视对多种病原体的筛查,降低某种病原体的漏检率,做到早筛查,及时诊治。
Objective:To analyze the infection population and characteristics of Chlamydia trachomatis,Ureaplas⁃ma urealyticum,and Mycoplasma genitalium among outpatients in Guangzhou,and to provide epidemiological reference for clinical diagnosis and treatment.Methods:A total of 1137 urogenital secretion or urine samples were collected fromoutpatients of Sun Yat⁃sen Memorial Hospital of Sun Yat⁃sen University from September 2021 to September 2022,and to analyze the nucleic acid testing results of the CT,UU and MG in the urogenital secretion of patients.Results:The positive rates of CT,UU and MG in outpatients in Guangzhou area were 4.05%(46/1137),31.05%(353/1137),1.50%(17/1137),and the positive rate of UU in female patients was significantly higher than that males,the difference was statistically significant(χ^(2)=28.676,P<0.001),the positive detection rate of MG in male patients was significantly higher than that of female,the difference was statistically significant(χ^(2)=6.236,P<0.05),There was no significant gen⁃der difference in CT positive detection rate.A total of 27 cases of mixed infection with two or three pathogens were detect⁃ed,and the positive rate of mixed infection was 2.37%(27/1137).The type of mixed infection in outpatients was mainly CT+UU.CT,UU,and MG infection populations were mainly distributed in the age group of 21-40,and among male pa⁃tients aged≤20 years old,CT,UU,and MG had a higher detection rate.Conclusion:The detection rate of CT,UU and MG in outpatients is high,and there is a phenomenon of mixed infection of various pathogens.In clinical diagnosis and treatment,it is necessary to pay attention to the screening of multiple pathogens,reduce the missed detection rate of certain pathogens,and achieve early screening,timely diagnosis and treatment.
作者
吴文钦
何寿富
李雪雪
WU Wen-qin;HE Shou-fu;Li Xue-xue(LaboratoryDepartment,Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University,Guangzhou,510000)
出处
《岭南急诊医学杂志》
2023年第4期333-335,共3页
Lingnan Journal of Emergency Medicine
关键词
沙眼衣原体
解脲脲原体
生殖支原体
泌尿生殖道感染
chlamydia trachomatis
ureaplasma urealyticum
mycoplasma genitalium
urogenital infection
