摘要
目的探讨经导管主动脉瓣置换术(TAVR)治疗重度主动脉瓣狭窄(AS)的效果及对心功能指标的影响。方法选取2020年7月至2021年4月我院收治的40例重度AS患者为研究对象,根据治疗方法不同将其分为外科主动脉瓣置换术(SAVR)组和TAVR组,各20例。SAVR组行SAVR治疗,TAVR组行TAVR治疗。比较两组的治疗效果。结果术后6个月,两组的主动脉瓣流速、主动脉瓣跨瓣峰值压差均降低,主动脉瓣瓣口面积均增大,且TAVR组优于SAVR组(P<0.05)。术后3 d,TAVR组的左心室射血分数(LVEF)高于SAVR组,左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、左心室后壁厚度(LVPWT)、左室舒张末期容积(LVEDV)及纽约心脏病协会(NYHA)心功能分级Ⅲ~Ⅳ级占比低于SAVR组(P<0.05)。两组的并发症总发生率比较,差异无统计学意义(P>0.05)。结论TAVR治疗重度AS的效果较好,可改善患者的瓣膜功能及心功能指标,值得临床应用。
Objective To explore the effect of transcatheter aortic valve replacement(TAVR)in the treatment of severe aortic stenosis(AS)and its influence on cardiac function indexes.Methods A total of 40 patients with severe AS admitted in our hospital from July 2020 to April 2021 were selected as the research objects.According to different treatment methods,the patients were divided into surgical aortic valve replacement(SAVR)group and TAVR group,with 20 cases in each group.The SAVR group was treated with SAVR,and the TAVR group was treated with TAVR.The therapeutic effects of the two groups were compared.Results At 6 months after operation,the aortic valve flow rate and peak pressure gradient aortic valve in the two groups decreased,the aortic valve orifice area increased,and those in the TAVR group were better than the SAVR group(P<0.05).At 3 d after operation,the left ventricular ejection fraction(LVEF)in the TAVR group was higher than that in the SAVR group,while the left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),left ventricular posterior wall thickness(LVPWT),left ventricular end diastolic volume(LVEDV)and the proportion of New York Heart Association(NYHA)cardiac function gradeⅢ-Ⅳin the TAVR group were lower than those in the SAVR group(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion TAVR is effective in the treatment of severe AS,it can improve the valve function and cardiac function indexes of patients,which is worthy of clinical application.
作者
张瑜
程维平
白兴万
康伟
ZHANG Yu;CHENG Weiping;BAI Xingwan;KANG Wei(Xi'an International Medical Center Hospital,Xi'an 710100,China)
出处
《临床医学研究与实践》
2023年第28期62-65,共4页
Clinical Research and Practice
