摘要
目的 分析河北省助产机构实验室乙型病毒性肝炎(简称“乙肝”)检测服务能力,为河北省开展消除乙肝母婴传播工作提供政策依据。方法 于2021年4月至2021年9月采用调查问卷和实地调查相结合的方法,收集河北省2020年各级助产机构实验室乙肝检测服务能力资料,包括实验室资质、检测方法和乙肝病毒载量检测、实验室人员职称学历等。所有资料采用Excel 2021软件进行数据整理和分析。结果 河北省97.92%的助产机构可开展乙肝病毒表面抗原检测,97.40%的助产机构可开展乙肝五项血清学标志物检测;不同级别助产机构乙肝五项血清学标志物检测方法不同,省级助产机构以化学发光免疫分析法为主,占50.00%,乡级助产机构以胶体金方法为主,占57.14%。97.92%的助产机构可开展肝功能检测,27.27%的助产机构可进行乙型肝炎病毒(Hepatitis B virus, HBV)DNA定量检测,其中以省级助产机构占比最高,为75.00%。结论 河北省助产机构实验室乙肝五项检测覆盖率较高,HBV DNA定量检测能力不足。建议加强县、乡级助产机构乙肝病毒载量实验室建设,为预防乙肝母婴传播提供保障。
Objective To analyze the testing service capacity of laboratory hepatitis B(HB)in midwifery institutions of Hebei Province,and to provide a policy basis for the elimination of mother-to-child transmission of hepatitis B in Hebei Province.Methods From April 2021 to September 2021,a combination of questionnaire and field survey was adopted to collect laboratory hepatitis B testing service capacity data of midwifery institutions at all levels in Hebei Province in 2020,including laboratory qualification,testing method,Hepatitis B virus load testing,and professional title and education of laboratory personnel.All data were collated and analyzed using Excel 2021 software.Results There were 97.92%of midwifery institutions in Hebei Province can carry out hepatitis B surface antigen tests,and 97.40%for five-item serological markers tests of hepatitis B.Different midwifery institutions at different levels used different methods for five-item serological markers tests of hepatitis B.The provincial midwifery institutions mainly used chemiluminescence immunoassay,accounting for 50.00%,and the township midwifery institutions mainly used colloidal gold method,accounting for 57.14%.Liver function tests were available in 97.92%of midwifery institutions,and quantitative Hepatitis B virus(HBV)DNA tests were available in 27.27%of midwifery institutions,with the highest percentage of 75.00%in provincial midwifery institutions.Conclusion The coverage rate of the five-item serological markers tests of hepatitis B in in laboratory of midwifery institutions in Hebei Province is high,but the capacity of detection and quantitation of HBV DNA is insufficient.It is suggested to strengthen the construction of Hepatitis B virus load laboratory in county and township midwifery institutions to provide guarantee for preventing mother-to-child transmission of hepatitis B.
作者
钱立杰
李雅丽
李林
孙兆阳
马倩
许长田
QIAN Lijie;LI Yali;LI Lin;SUN Zhaoyang;MA Qian;XU Changtian(Hebei Maternal and Child Health Care Center,Shijiazhuang,Hebei 050031,China;不详)
出处
《医学动物防制》
2023年第9期905-909,共5页
Journal of Medical Pest Control
基金
中国性病艾滋病防治协会·艾伯维妇幼关爱及预防母婴传播基金项目(2020PMTCT-W9b)。
关键词
助产机构
乙型肝炎
母婴传播
实验室检测
调查
分析
Midwifery institution
Hepatitis B
Mother-to-child transmission
Laboratory testing
Investigation
Analysis
