摘要
背景:在经颅磁刺激临床实际应用中,是否能准确瞄准刺激脑区可影响经颅磁刺激的实际治疗效果。近年来,随着神经导航系统、移动式增强现实技术的发展,以及多种不同模态磁共振成像数据分析方法的出现,刺激靶区定位的准确性和靶区选择的优化有望得到进一步的提高。目的:综述基于磁共振成像的影像导航定位原理及在经颅磁刺激中的应用,归纳不同模态磁共振成像数据分析在指导经颅磁刺激靶区选择上的作用。方法:应用计算机在PubMed、中国知网和万方数据库检索相关文献,以“transcranial magnetic stimulation,coil positioning,neuronavigation,augmented reality,magnetic resonance imaging,经颅磁刺激,线圈定位,神经导航,增强现实,核磁共振成像,原理”为主要检索词,最终纳入63篇文献进行分析。结果与结论:①传统经颅磁刺激线圈放置方法中,“5 cm规则”、国际脑电10-20定位法最为常用,这些方法具有简便、经济的优点,但过于依赖操作者的经验,存在不同操作者的技术差异。②基于立体定向技术发展而来的神经导航系统是目前可视化程度及准确度最高的辅助经颅磁刺激线圈放置的引导方式,它通过MRI数据采集、脑三维重建、头模配准及立体几何定位等步骤来实现可视化定位,具有较高的临床治疗及科研应用价值,但因其设备较为昂贵,目前在医疗机构中尚未普及。③对于不同层次的医疗单位,移动式移动式增强现实技术不失为一种经济、高效的神经导航系统替代方案,它通过磁共振成像数据采集、构建二维/三维图像、虚拟图像与真实脑图像叠加来实现头皮下脑组织可视化定位,具有直观性强、成本低廉的优势,可在基层医疗单位推广应用。④尽管相对脑电10-20定位策略,可视化定位的临床疗效优越性目前尚未充分体现,但随着研究者对人脑多种不同模态磁共振成像扫描数据�
BACKGROUND:In clinical application,the therapeutic effect of transcranial magnetic stimulation depends on the ability to accurately target the areas of the brain that need to be stimulated.In recent years,with the development of neuronavigation systems,mobile augmented reality technology,and the new methods of processing magnetic resonance imaging(MRI)data,the accuracy of stimulus target localization and the optimization of target selection are expected to improve further.OBJECTIVE:To review the principle of MRI-based image navigation and its application in transcranial magnetic stimulation and summarize the roles of different modal MRI data analyses in guiding the selection of target areas for transcranial magnetic stimulation.METHODS:An online computer search for relevant literature was performed in PubMed,CNKI database and WanFang database,with the keywords“transcranial magnetic stimulation,coil positioning,neuronavigation,augmented reality,magnetic resonance,theory.”Finally,63 documents were included for review.RESULTS AND CONCLUSION:Among the traditional methods of positioning transcranial magnetic stimulation coils,the“5 cm rule”and the international electroencephalogram 10-20 positioning method are the most commonly used.These methods have the advantages of simplicity and economy,but they rely too much on the operator’s experience and there were technical differences between operators.The neuronavigation system,which is based on stereotactic technology,is the guiding method for positioning transcranial magnetic stimulation coils with the highest visual degree and accuracy.It achieves visual positioning through MRI data acquisition,3D brain reconstruction,head model registration and stereogeometric positioning.It has high application value in clinical treatment and scientific research,but it cannot be promoted in medical institutions due to its high cost.For various medical institutions,mobile augmented reality is a cost-effective and efficient alternative to the neuronavigation system,which achie
作者
王荔
陈鹏
韦秀英
卢阳佳
赖思嘉
王凯华
Wang Li;Chen Peng;Wei Xiuying;Lu Yangjia;Lai Sijia;Wang Kaihua(Department of Neurology,International Zhuang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530200,Guangxi Zhuang Autonomous Region,China;Department of Radiology,International Zhuang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530200,Guangxi Zhuang Autonomous Region,China;College of Acupuncture and Massage,Guangxi University of Chinese Medicine,Nanning 530200,Guangxi Zhuang Autonomous Region,China)
出处
《中国组织工程研究》
CAS
北大核心
2024年第26期4234-4241,共8页
Chinese Journal of Tissue Engineering Research
基金
广西中医药大学博士科研启动基金项目(2020BS031),项目负责人:王荔
广西壮族自治区中医药局自筹经费项目(20210393),项目负责人:王荔
广西高校中青年教师科研基础能力提升项目(2021KY0308),项目负责人:王荔
中国民族医药学会科研项目(2022M1112-140201),项目负责人:王荔
广西中医药脑病重点学科(GZXK-Z-20-14),项目负责人:王凯华
广西中医药大学第二批“岐黄工程”高层次人才团队培育项目(2021008),项目负责人:王凯华。
关键词
经颅磁刺激
线圈定位
靶区选择
脑三维重建
立体定向技术
神经导航系统
移动式增强现实
脑3D解剖成像
脑功能成像
脑结构成像
transcranial magnetic stimulation
coil positioning
target selection
3D brain reconstruction
stereotactic technique
neuronavigation system
mobile augmented reality
brain 3D anatomical imaging
brain function imaging
brain structure imaging
