摘要
有机化合物的命名,尤其是一些复杂药物分子的化学名,常常需要标明额外氢与增加氢。《有机化合物命名原则2017》(简称CCS 2017)对2者的使用作出了规范,但缺乏具体使用规则,并且操作示例较少。基于CCS 2017命名原则,结合Nomenclature of Organic Chemistry:IUPAC Recommendations and Preferred Names2013(简称IUPAC 2013)和《中国药典2020》,详细阐释了额外氢和增加氢的含义,并通过示例化合物命名实操,讨论并总结了具体的使用规则和方法。同时,比较了这3大命名法中有关额外氢和增加氢的命名规则,辨析了它们的迥异之处,并对CCS 2017命名原则在药物中文化学名中的应用提出了建议。
The nomenclature of organic compounds,especially the naming of complex drug molecules,often requires indication of the extra hydrogen and added hydrogen.Their use in Chinese is regulated by the principles for naming organic compounds in the book Nomenclature of Organic Compounds 2017(CCS 2017),but few specific rules for use and operational examples in it.Based on CCS 2017 and combined with Nomenclature of Organic Chemistry:IUPAC Recommendations and Preferred Names 2013(IUPAC 2013)and Pharmacopoeia of the People's Republic of China 2020,the concrete implications of extra hydrogen and added hydrogen were explained in detail.The general usage rules and methods for them were illustrated and summarized through the naming of some specific examples.Furthermore,the naming conventions for extra hydrogen and added hydrogen in above three nomenclatures were compared,and their inconsistencies and differences were distinguished.Some suggestions about the application of CCS 2017 principles to the chemical names of drugs were proposed as well.
作者
梅青刚
王淳
谭承佳
姜立春
MEI Qing-Gang;WANG Chun;TAN Cheng-Jia;JIANG Li-Chun(School of Life Science and Biotechnology,Mianyang Teachers'College,Mianyang 621000,China;Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610041,China)
出处
《化学教育（中英文）》
CAS
北大核心
2023年第16期20-29,共10页
Chinese Journal of Chemical Education
基金
四川省教育科研2021年度重点课题(SCJG21A020)
绵阳师范学院教学改革研究项目(Mnu-JY210132)。
关键词
有机化合物
系统命名
CCS
2017规则
额外氢
增加氢
organic compounds
systematic nomenclature
CCS 2017 rules
extra hydrogen
added hydrogen
