摘要
目的 分析万古霉素运用在脓毒症合并急性肾损伤患者的临床价值。方法 回顾性分析2020年12月—2021年12月在吉林省人民医院接受治疗的66例脓毒症合并急性肾损伤患者的临床资料,按照治疗方法分为两组,各33例。参照组应用常规治疗,研究组在常规治疗的基础上,给予盐酸万古霉素治疗。比较两组炎症指标、肾功能指标、治疗效果及并发症发生情况。结果 研究组的并发症发生率(3.03%)低于参照组(30.30%),差异有统计学意义(P<0.05)。研究组的治疗有效率(96.97%)高于参照组(63.64%),差异有统计学意义(χ^(2)=11.590,P=0.001)。结论 给予脓毒症合并急性肾损伤患者万古霉素治疗,可降低其并发症发生率,预防感染,帮助患者加快自身的恢复。
Objective To analyze the clinical value of vancomycin use in patients with sepsis combined with acute kidney injury.Methods The clinical data of 66 patients with sepsis complicated with acute kidney injury who received treatment in Jilin Provincial People's Hospital from December 2020 to December 2021 were retrospectively analyzed,and were divided into two groups according to treatment methods,with 33 cases in each group.The reference group received conventional treatment,and the study group was given vancomycin hydrochloride on the basis of conventional treatment.The inflammatory indexes,renal function indexes,therapeutic effects and complications were compared between the two groups.Results The complication rate of the study group(3.03%) was lower than that of the reference group(30.30%),and the difference was statistically significant(P<0.05).The effective rate of the study group(96.97%) was higher than that of the control group(63.64%),and the difference was statistically significant(χ^(2)=11.590,P=0.001).Conclusion Vancomycin therapy in patients with sepsis combined with acute kidney injury can reduce the incidence of complications,prevent infection,and help patients speed up their recovery.
作者
于欣
王潇然
YU Xin;WANG Xiaoran(Department of Critical Care Medicine,Jilin Provincial People's Hospital,Changchun,Jilin Province,130000 China;Department of Urology,Jilin Provincial People's Hospital,Changchun,Jilin Province,130000 China)
出处
《中外医疗》
2023年第20期110-113,共4页
China & Foreign Medical Treatment
基金
吉林省卫生健康科技能力提升项目(2021 LC068)。
