摘要
目的探讨布托啡诺复合靶控输注丙泊酚麻醉用于宫腔镜电切术的临床效果。方法选取2019年2月至2020年2月于本院行宫腔镜电切术的92例患者作为研究对象,随机分为对照组与观察组,每组46例。对照组采用芬太尼复合靶控输注丙泊酚麻醉,观察组采用布托啡诺复合靶控输注丙泊酚麻醉,比较两组麻醉前后血氧饱和度(SpO_(2))、平均动脉压(MAP)、心率(HR)、视觉模拟评分法(VAS)评分和不良反应发生情况。结果麻醉后,两组SpO_(2)均高于麻醉前,且观察组高于对照组,差异有统计学意义(P<0.05);麻醉后,两组MAP和HR均低于麻醉前,但观察组高于对照组,差异有统计学意义(P<0.05)。两组VAS组间、时间、交互比较差异有统计学意义(P<0.05);组内比较:麻醉后5 min,两组VAS评分均低于麻醉前30 min(P<0.05),麻醉后15 min,两组VAS评分均高于麻醉后5 min、麻醉前30 min,差异有统计学意义(P<0.05);组间比较:麻醉前30 min,两组VAS评分比较差异无统计学意义,麻醉后5、15 min,观察组VAS评分均明显低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义。结论布托啡诺复合靶控输注丙泊酚麻醉在宫腔镜电切术中应用效果良好,可完全满足镇静镇痛的要求,停药后患者可迅速苏醒,值得临床推广应用。
Objective To investigate the clinical effect of butorphanol combined with target controlled infusion of propofol anesthesia in hysteroscopic electric resection.Methods 92 patients who underwent hysteroscopic resection in our hospital from February 2019 to February 2020 were selected as the study subjects,and they were randomly divided into the control group and the observation group,with 46 cases in each group.The control group was anesthetized with fentanyl combined with target-controlled infusion of propofol,while the observation group was anesthetized with butorphanol combined with target-controlled infusion of propofol,the levels of pulse oxygen saturation(SpO_(2)),mean arterial pressure(MAP),heart rate(HR),and visual analogue scale(VAS)scores before and after anesthesia and adverse reactions were compared between two groups.Results After anesthesia,the SpO_(2) levels of the two groups were higher than that before anesthesia,and the observation group was higher than the control group,the differences were statistically significant(P<0.05);after anesthesia,the MAP and HR of the two groups were lower than those before anesthesia,but the observation group was higher than the control group,the differences were statistically significant(P<0.05).There were statistically significant differences in VAS score between two group,time and interaction between the two groups(P<0.05);intra-group comparison:5 min after anesthesia,VAS scores of both groups were lower than 30 min before anesthesia,15 min after anesthesia,VAS scores of both groups were higher than 5 min after anesthesia and 30 min before anesthesia,the difference was statistically significant(P<0.05);intra-group comparison:30 min before anesthesia,there was no statistical significance in VAS score between the two groups;5 and 15 min after anesthesia,VAS score of the observation group was significantly lower than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions
作者
黄群英
HUANG Qunying(Department of Anesthesiology,Fuzhou Maternal and Child Health Hospital,Fuzhou,Jiangxi,344300,China)
出处
《当代医学》
2023年第7期32-35,共4页
Contemporary Medicine
基金
江西省卫生计生委科技计划项目(20187145)。
关键词
布托啡诺
靶控输注丙泊酚
麻醉
宫腔镜电切术
Butorphanol
Target-controlled infusion of propofol
Anesthesia
hysteroscopic electric resection
