摘要
目的探究宫腔镜下子宫内膜息肉切除术后应用左炔诺孕酮宫内节育系统(LNG-IUS)预防子宫内膜息肉(EP)复发的临床疗效。方法选取2019年3月至2020年3月于本院接受宫腔镜下EP切除术的100例EP患者作为研究对象,根据术后干预方式不同分为观察组与对照组,每组50例。观察组术后行LNG-IUS干预治疗,对照组术后口服地屈孕酮干预治疗,比较两组术后复发情况、手术前后子宫内膜厚度、术后血红蛋白指标。结果观察组术后3、6、12个月复发率均低于对照组,差异有统计学意义(P<0.05)。两组子宫内膜厚度组间、时间、交互比较差异有统计学意义(P<0.05);两组术后各时间点子宫内膜厚度均薄于前一时间点,且观察组薄于对照组,差异有统计学意义(P<0.05)。两组血红蛋白水平组间、时间、交互比较差异有统计学意义(P<0.05);两组术后各时间点血红蛋白水平均高于前一时间点,且观察组高于对照组,差异有统计学意义(P<0.05)。结论EP切除术后行LNG-IUS干预治疗,能明显降低患者EP的复发率,改善子宫内膜厚度,提高血红蛋白水平,值得临床推广应用。
Objective To study the clinical efficacy of levonorgestrel intrauterine birth control system(LNG-IUS)in preventing recurrence of endometrial polyps after hysteroscopic endometrial polypectomy(EP).Methods A total of 100 patients with endometrial polyps who underwent hysteroscopic EP in our hospital from March 2019 to March 2020 were selected as the research subjects,and they were divided into the observation group and the control group according to different postoperative intervention methods,with 50 cases in each group.The observation group was treated with LNG-IUS intervention after operation,and the control group was treated with oral dydrogesterone intervention after operation,the postoperative recurrence,endometrial thickness before and after operation,and postoperative hemoglobin index were compared between the two groups.Results The recurrence rates in the observation group at 3,6 and 12 months after operation were lower than those in the control group,and the differences were statistically significant(P<0.05).There were significant differences in endometrial thickness between the two groups of group,time points and interaction(P<0.05).The endometrial thickness of the two groups at each time point after operation was thinner than that at the previous time point,and the observation group was thinner than the control group,the differences were statistically significant(P<0.05).There were significant differences in hemoglobin levels between the two groups of group,time points and interaction(P<0.05);the hemoglobin levels of the two groups at each time point after operation were higher than those at the previous time point,and the observation group was higher than the control group,the differences were statistically significant(P<0.05).Conclusion LNG-IUS intervention after EP resection can significantly reduce the recurrence rate of EP,improve endometrial thickness and hemoglobin level,which is worthy of clinical promotion and application.
作者
利园梦
LI Yuanmeng(Department of Gynecology,Jiujiang First People's Hospital,Jiujiang,Jiangxi,332000,China)
出处
《当代医学》
2023年第18期154-156,共3页
Contemporary Medicine
关键词
子宫内膜息肉
切除手术
左炔诺孕酮
宫内节育
Endometrial polyp
Excision
Levonorgestrel
Intrauterine birth control
