摘要
目的探讨留置深静脉管充分引流结合聚桂醇硬化治疗肝肾囊肿的临床疗效。方法选取2018年4月至2020年4月于本院肿瘤内科就诊92例肝肾囊肿患者作为研究对象,按照随机单双号法分为观察组与对照组,每组46例。观察组采用置入单腔深静脉管充分引流联合注入聚桂醇硬化治疗,对照组采用置入单腔深静脉管充分引流联合注入无水乙醇治疗,比较两组囊肿体积缩小率、临床疗效、术中不良反应和随访复发情况。结果两组囊肿体积缩小率组间、时间比较差异有统计学意义(P<0.05),两组囊肿体积缩小率交互比较差异无统计学意义;术后6、12个月,两组囊肿体积缩小率均高于术后3个月,差异有统计学意义(P<0.05),两组术后6个月与12个月囊肿体积缩小率比较差异无统计学意义;术后3、6、12个月,观察组囊肿体积缩小率均高于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,但组间比较差异无统计学意义。观察组不良反应发生率为6.52%,低于对照组的23.91%,差异有统计学意义(P<0.05);观察组复发率为4.35%,对照组为8.70%,组间比较差异无统计学意义。结论留置深静脉管充分引流结合聚桂醇硬化治疗肝肾囊肿疗效较理想,不良反应和复发率较低。
Objective To investigate the clinical effect of deep venous catheter drainage combined with lauromacrogol sclerotherapy for hepatorenal cyst.Methods 92 patients with hepatorenal cysts treated in the department of Oncology of our hospital from April 2018 to April 2020 were selected as the study subjects,and they were divided into the observation group and the control group according to random odd-even number method,with 46 cases in each group.The observation group was treated with full drainage of single-lumen deep venous catheter combined with the injection of lauromacrogol sclerotherapy,while the control group was treated with full drainage of single-lumen deep venous catheter combined with the injection of anhydrous alcohol,the rate of cyst volume reduction,clinical efficacy,intraoperative adverse reactions and follow-up recurrence were compared between the two groups.Results There were statistically significant differences in the rate of cyst volume reduction between groups of group,time points(P<0.05),while there were no statistically significant differences in the rate of cyst volume reduction the interaction between the two groups;at 6 and 12 months after surgery,the rate of cyst volume reduction of the two groups was higher than that at 3 months after surgery,the difference was statistically significant(P<0.05),and there was no statistically significant difference in the rate of cyst volume reduction at 6 months and 12 months after surgery between the two groups;at 3,6 and 12 months after surgery,the rate of cysts volume reduction in the observation group were significantly higher than that in the control group,and the differences were statistically significant(P<0.05).The total effective rate in the observation group was higher than that in the control group,but the difference was not statistically significant.The incidence of adverse reactions in the observation group was 6.52%,which was lower than 23.91%in the control group,and the difference was statistically significant(P<0.05).The recurrence rate was
作者
饶珣坚
熊卿
韩曲
RAO Xunjian;XIONG Qing;HAN Qu(Department of Ultrasound,Fengcheng People's Hospital,Yichun,Jiangxi,331100,China;Department of General surgery,Fengcheng People's Hospital,Yichun,Jiangxi,331100,China)
出处
《当代医学》
2023年第19期137-139,共3页
Contemporary Medicine
关键词
肝肾囊肿
单腔深静脉管
聚桂醇
无水乙醇
硬化治疗
Hepatorenal cyst
Single-lumen deep venous catheter
Lauromacrogol
Anhydrous ethanol
Sclerotherapy