摘要
目的探究CT影像组学特征预测肝细胞癌术后早期复发的价值。方法回顾性分析项城市中医院接受肝切除术的110例肝细胞癌患者CT影像资料,以7∶3的比例按照术后是否早期复发将其分为训练组(77例)和验证组(33例)。提取术后早期复发患者影像组学特征,使用LASSO降维和logistic回归建立影像组学特征预测模型,评估模型预测价值。结果经筛选得到6个与肝细胞癌术后早期复发相关性最强的影像组学特征,ROC曲线结果显示训练组预测肝细胞癌术后早期复发的AUC为0.865,敏感度、特异度分别为85.48%、80.95%;验证组预测肝细胞癌术后早期复发的AUC为0.862,敏感度、特异度分别为88.71%、84.13%。结论基于CT影像组学特征构建的肝细胞癌术后早期复发预测模型有助于预测肝细胞癌术后复发情况,预测价值较高。
Objective To explore the predictive value of CT radiomics characteristics for early recurrence after hepatocellular carcinoma surgery.Methods The CT imaging data of 110 patients with hepatocellular carcinoma who underwent hepatectomy was retrospectively analyzed.According to the presence or absence of postoperative early recurrence,the data were divided into training group(77 cases)and validation group(33 cases).The radiomics characteristics of patients with early recurrence were analyzed.LASSO regression and Logistic regression were used to construct a prediction model,and its predictive value was evaluated.Results There were 6 radiomics characteristics associated with postoperative early recurrence.ROC curve analysis showed that the AUC,sensitivity and specificity of the training group to predicting postoperative early recurrence were 0.865,85.48%and 80.95%.The AUC,sensitivity and specificity of the validation group were 0.862,88.71%and 84.13%.Conclusion The prediction model constructed based on CT radiomics characteristics is helpful for predicting early recurrence after hepatocellular carcinoma surgery.
作者
王力
张文涛
牛莎莎
WANG Li;ZHANG Wentao;NIU Shasha(Xiangcheng Hospital of Traditional Chinese Medicine,Zhoukou,466200)
出处
《实用癌症杂志》
2023年第9期1510-1514,共5页
The Practical Journal of Cancer
关键词
影像组学特征
肝细胞癌
肝切除术
早期复发
预测价值
Radiomics Characteristic
Hepatocellular Carcinoma
Hepatectomy
Early Recurrence
Predictive Value
