摘要
目的探讨卵巢成年型粒层细胞瘤的临床病理特点。方法收集无锡市妇幼保健院的19例卵巢成年型粒层细胞瘤的病例资料,分析卵巢成年型粒层细胞瘤的临床病理特点。结果肿瘤发病年龄29~77岁,直径2~17 cm;主诉阴道出血或月经紊乱10例,腹胀1例,9例无明显临床症状;FIGO分期均为Ⅰ期,形态结构多样;EMA、CgA、Syn均为阴性,Calretinin阳性率为94.7%,a-抑制素阳性率为89.5%;子宫内膜病变率为54.5%,均无复发转移。结论卵巢成年型粒层细胞瘤较为罕见,易伴发子宫内膜病变,组织形态多样,需与多种疾病鉴别诊断。
Objective To explore the clinical and pathological characteristics of adult granulosa cell tumors of the ovary.Methods Collect 19 cases of ovarian adult granulosa cell tumor from Wuxi maternal and child health hospital,and analyze the clinical and pathological characteristics of ovarian adult granulosa cell tumor.Results The age of onset of the tumor was 29-77 years old,with a diameter of 2-17 cm;10 cases complained of vaginal bleeding or menstrual disorders,1 case of abdominal distension,and 9 cases had no obvious clinical symptoms;The FIGO stages are all stage Ⅰ,with diverse morphological structures;EMA,CgA,and Syn were all negative,with a positive rate of 94.7%for Calletinin and 89.5%for a-inhibin;The rate of endometrial lesions reached 54.5%,with no recurrence or metastasis.Conclusion Adult granulosa cell tumors of the ovary are relatively rare,easily accompanied by endometrial lesions,with diverse tissue morphology,and need to be differentiated and diagnosed with various diseases.
作者
程静
赵华
Cheng Jing;Zhao Hua(Department of Pathology,Wuxi Maternal and Child Health Hospital,Wuxi 214002,China)
出处
《实用妇科内分泌电子杂志》
2023年第12期13-15,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
卵巢成年型粒层细胞瘤
临床特点
病理诊断
Adult granulosa cell tumor of the ovary
Clinical characteristics
Pathologic diagnosis