摘要
目的 研究多囊卵巢综合征(PCOS)患者发生先兆流产的影响因素。方法 选取西安市第四医院收治的186例PCOS患者,根据是否合并先兆流产将其分为先兆流产组(93例,合并先兆流产)和正常组(93例,不合并先兆流产)。比较两组的临床资料;分析PCOS患者发生先兆流产的影响因素;分析肥胖、睾酮(T)、空腹胰岛素(FINS)、空腹血糖(FPG)、胰岛素抵抗(IR)、凝血因子Ⅷ(FⅧ)对PCOS患者发生先兆流产的诊断价值。结果 先兆流产组的肥胖占比、T、FINS、FPG、IR、FⅧ高于正常组,差异具有统计学意义(P<0.05)。二元Logistic回归分析结果显示,肥胖、T、FINS、FPG、IR、FⅧ均为PCOS患者发生先兆流产的危险因素(P<0.05)。T对PCOS患者发生先兆流产的诊断价值最高。结论 肥胖、T、FINS、FPG、IR、FⅧ均与PCOS患者先兆流产的发生明显相关,其中T对PCOS患者发生先兆流产的诊断价值最高。临床中应加强对具有上述高风险因素PCOS患者的孕期监测,以及时采取措施降低先兆流产发生风险,改善患者的妊娠结局。
Objective To study the influencing factors of threatened abortion in patients with polycystic ovary syndrome(PCOS).Methods A total of 186 PCOS patients admitted in Xi'an Fourth Hospital were selected and divided into threatened abortion group(93 cases,combined with threatened abortion)and normal group(93 cases,not combined with threatened abortion)according to whether the patients were combined with threatened abortion.The clinical data of the two groups were compared;the influencing factors of threatened abortion in PCOS patients was analyzed;the diagnostic value of obesity,testosterone(T),fasting insulin(FINS),fasting plasma glucose(FPG),insulin resistance(IR)and coagulation factorⅧ(FⅧ)in the occurrence of threatened abortion in PCOS patients were analyzed.Results The proportion of obesity,T,FINS,FPG,IR and FⅧin the threatened abortion group were higher than those in the normal group,and the differences were statistically significant(P<0.05).Binary Logistic regression analysis results showed that obesity,T,FINS,FPG,IR and FⅧwere risk factors for threatened abortion in PCOS patients(P<0.05).T has the highest diagnostic value for the occurrence of threatened abortion in PCOS patients.Conclusion Obesity,T,FINS,FPG,IR and FⅧare significantly correlated with the occurrence of threatened abortion in PCOS patients,among which T has the highest diagnostic value for threatened abortion in PCOS patients.Clinically,pregnancy monitoring of PCOS patients with the above high-risk factors should be strengthened,and timely measures should be taken to reduce the risk of threatened abortion,and improve the pregnancy outcome of patients.
作者
李霞
陈若兰
LI Xia;CHEN Ruolan(Gynecology and Obstetrics Department,Xi'an People's Hospital/Xi'an Fourth Hospital,Xi'an 710004,China)
出处
《临床医学研究与实践》
2023年第24期14-17,共4页
Clinical Research and Practice
关键词
多囊卵巢综合征
先兆流产
临床特征
凝血功能
polycystic ovary syndrome
threatened abortion
clinical features
coagulation function
