摘要
目的探讨红细胞平均体积(Mean Corpuscular Volume,MCV)、平均红细胞血红蛋白量(Mean Corpuscular Hemoglobin,MCH)、红细胞分布宽度(Red blood cell Distribution Width,RDW)及血清铁蛋白(Serum Ferritin,SF)应用在地中海贫血及与缺铁性贫血鉴别中的灵敏度分析。方法选取2018年3月至2020年8月在本研究就诊的地中海贫血和缺铁性贫血患者,各46例。比较两组MCV、MCH、RDW及SF水平及联合诊断结果(敏感度、特异度及准确度)。结果地中海贫血组MCV、RDW显著低于缺铁性贫血组,地中海贫血组MCH、SF显著高于缺铁性贫血组,P<0.05。MCV、MCH、RDW、SF联合检测后,两组灵敏度、特异度及准确度比较,P>0.05。结论地中海贫血及与缺铁性贫血鉴别中,MCV、MCH、RDW及SF联合检测诊断价值高,值得推广。
Obiective To investigate Mean Corpuscular Volume(MCV)and Mean Corpuscular Hemoglobin(Mean Corpuscular Hemoglobin).Sensitivity analysis of the application of MCH,Red blood cell Distribution Width(RDW)and Serum Ferritin(SF)in the differentiation of thalassemia and iron deficiency anemia.Methods From March 2018 to August 2020,46 patients with thalassemia and 46 patients with iron deficiency anemia who were treated in this study were selected.The levels of MCV,MCH,RDW and SF and the combined diagnosis results(sensitivity,specificity and accuracy)were compared between the two groups.Results MCV and RDW in the thalassemia group were significantly lower than those in the iron deficiency anemia group,while MCH and SF in the thalassemia group were significantly higher than those in the iron deficiency anemia group,P<0.05.After MCV,MCH,RDW and SF combined detection,the sensitivity,specificity and accuracy of the two groups were compared,P>0.05.Conclusion The combined detection of MCV,MCH,RDW and SF has high diagnostic value in the differentiation of thalassemia and iron deficiency anemia.
作者
周莉
刘梦园
郑玥
ZHOU Li;LIU Meng-yuan;ZHENG Yue(Laboratory Department of Kaifeng Maternal and Child Health Hospital,Kaifeng 475000,Henan Province,China)
出处
《罕少疾病杂志》
2023年第8期6-7,共2页
Journal of Rare and Uncommon Diseases
