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氯沙坦钾片联合利拉鲁肽注射液治疗早期糖尿病肾病的临床效果观察 被引量:1

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摘要 目的探讨氯沙坦钾片联合利拉鲁肽注射液治疗早期糖尿病肾病的临床效果。方法选取收治的糖尿病肾病患者66例,依据随机数字表法分成对照组与研究组各33例,对照组予氯沙坦钾片治疗,研究组予氯沙坦钾片联合利拉鲁肽注射液治疗,比较治疗前后两组血糖指标[空腹血糖(FPG)、餐后2 h血糖(2 hPG)及糖化血红蛋白(HbA1c)]、血清肾功能指标[24 h微量蛋白尿(mAlb)、尿蛋白肌酐比值(UACR)及血清胱抑素C(CysC)]及血清炎性因子[血清C反应蛋白(CRP)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)]水平。结果治疗前,两组血糖指标、血清肾功能指标及炎性因子水平无显著差异(P>0.05);治疗后,两组血糖指标、肾功能指标及炎性因子水平均较治疗前好转,且研究组各血清指标优于对照组(P<0.05)。结论早期糖尿病肾病采用氯沙坦钾片具有一定临床效果,但联合利拉鲁肽注射液治疗效果更佳,可更加有效地改善患者血糖水平、保护肾功能,降低机体炎性反应。
出处 《现代诊断与治疗》 CAS 2023年第9期1345-1347,共3页 Modern Diagnosis and Treatment
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