摘要
目的观察穴位埋线辅助治疗对超重或肥胖伴2型糖尿病患者的临床疗效评价。方法将60例超重或肥胖伴2型糖尿病患者按照1∶1随机分为观察组和对照组。对照组予口服盐酸二甲双胍治疗,观察组在对照组基础上加用穴位埋线治疗,每周埋线1次,两组均连续治疗8周,并于治疗后8周随访。分别于第0周,第8周,第16周评价2组患者空腹血糖(FBG)、餐后2 h血糖(PBG)、糖化血红蛋白(HbAlc)、肥胖指标,并评定临床疗效。结果1)两组的FPG、PBG、HbAlc水平在第8周,16周时均较第0周下降,且观察组优于对照组(P<0.05);2)两组的体质量指数(BMI)、腰围(WC)、腰臀比(WHR)在第8周,16周时均较第0周下降,且观察组BMI优于对照组(P<0.05);3)两组的不良事件发生率均较低,差异无统计学意义(P>0.05)。结论穴位埋线配合二甲双胍治疗能有效改善超重或肥胖伴2型糖尿病患的FPG、PBG、HbAlc水平、减轻体重,具有较好的安全性,疗效优于单纯二甲双胍治疗。
Objective To observe the clinical effect of acupoint catgut embedding therapy on overweight or obese patients with type 2 diabetes mellitus.Methods 60 cases of overweight or obesity patients with type 2 diabetes mellitus were randomly divided into observation group and control group according to 1∶1.The control group was treated with oral metformin hydrochloride,and the observation group was treated with acupoint catgut embedding on the basis of the control group,once a week.Both groups were treated for 8 weeks,and followed up for 8 weeks after treatment.Fasting blood glucose(FBG),2-hour postprandial blood glucose(PBG),glycosylated hemoglobin(HbAlc)and obesity were evaluated at week 0,week 8 and week 16,and the clinical efficacy was evaluated.Results①The levels of FPG,PBG and HbAlc in the two groups were decreased at week 8 and 16 compared with week 0,and the observation group was better than the control group(P<0.05).②The body mass index(BMI),waist circumference(WC)and waist-to-hip ratio(WHR)of the two groups at 8 and 16 weeks were decreased compared with those at 0 weeks,and the BMI of the observation group was better than that of the control group(P<0.05).③The incidence of adverse events in the two groups was lower,and the difference was not statistically significant(P>0.05).Conclusion Acupoint catgut embedding combined with metformin treatment can effectively improve the levels of FPG,PBG,HbAlc and reduce body weight in overweight or obesity patients with type 2 diabetes mellitus,with good safety and better efficacy than metformin alone.
作者
周雨雨
杨硕
熊琳琳
蔡雨若
方利
莫倩
ZHOU Yuyu;YANG Shuo;XIONG Linlin;CAI Yuruo;FANG Li;MO Qian(Guizhou University of Traditional Chinese Medicine,Guiyang 550002,China;The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550003,China)
出处
《云南中医药大学学报》
2023年第4期11-15,24,共6页
Journal of Yunnan University of Chinese Medicine
基金
国家自然科学基金项目(81560798)
贵州省科技基金项目(黔科合[2020]1Y363号)。
关键词
穴位埋线
二甲双胍
超重
肥胖
2型糖尿病
acupoint catgut embedding
metformin
overweight
obesity
type 2 diabetes mellitus
