摘要
早产是一种常见的产科并发症,也是围生期发病率和死亡率的常见原因。近年来,早产率呈上升趋势。硒是一种微量营养元素,越来越多的研究表明,妊娠期间硒状态与早产的发生发展密切相关。硒可能通过发挥抗氧化活性和抗炎等功能预防早产发生,具体机制尚不清楚。本综述将从早产的发生机制出发,对两者之间的关系进行讨论。
Preterm birth is a prevalent source of perinatal morbidity and mortality as well as a common obstetric problem.Preterm birth rates have risen in recent years.Selenium is a micronutrient,and further research has revealed a strong correlation between preterm birth development and selenium status throughout pregnancy.By acting as an antioxidant and an anti-inflammatory,selenium may prevent preterm delivery,albeit the exact process is still unknown.The relationship between the two will be discussed in this review starting with the mechanism of premature delivery.
作者
辛爽
蔡雁
XIN Shuang;CAI Yan(The Fourth Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150001,China)
出处
《中国优生与遗传杂志》
2023年第7期1522-1527,共6页
Chinese Journal of Birth Health & Heredity
关键词
早产
硒
氧化应激
炎症
免疫
preterm birth
selenium
oxidative stress
inflammation
immunity