摘要
肿瘤压迫或浸润性视神经病变是由于肿瘤生长直接或间接损伤视觉传导通路而导致的视神经功能障碍。本文总结了国内外文献,发现肿瘤压迫或浸润性视神经病变的发病机制主要为肿瘤直接压迫、继发颅内高压、癌细胞浸润、副肿瘤综合征及转移瘤,不同机制造成的损害程度不同,预后也不同。西医治疗以改善循环、营养神经为主,中医针药并行也能取得良好疗效,但仍缺乏临床观察验证疗效。掌握肿瘤压迫及浸润性视神经病变的中、西医发病机制,有助于医师开展中西医结合诊疗,发挥各自优势,惠及更多患者。
Tumor-induced or infiltrative optic neuropathy refers to visual impairment caused by direct or indirect damages to the visual pathway due to tumor growth.We summarizes the litera⁃ture both domestically and internationally and finds that the pathogenesis of tumor-induced or in⁃filtrative optic neuropathy mainly involves tumor compression,secondary intracranial hyperten⁃sion,cancer cells infiltration,paraneoplastic syndromes,and metastatic tumors.The degree of damage and prognosis varies from the specific mechanisms involved.Western Medicine treatments focus on improving circulation and providing neural nourishment,while Traditional Chinese Medi⁃cine(TCM)approaches combining acupuncture and herbal medicine have also shown promising therapeutic effects.However,there is still a lack of clinical trials to validate the efficacy of these treatments.Understanding the pathogenesis of tumor compression and infiltrative optic neuropathy from both Western Medicine and TCM perspectives can facilitate integrated diagnosis and treat⁃ment approaches,leveraging the advantages of each system to benefit more patients.
作者
周芷伊
王影
龙思羽
孙婉钰
焦文鑫
林冀鲁
ZHOU Zhiyi;WANG Ying;LONG Siyu;SUN Wanyu;JIAO Wenxin;LIN Jilu(Eye Hospital,China Academy of Chinese Medical Sciences,Beijing 100040,China)
出处
《中国中医眼科杂志》
2023年第8期785-788,共4页
China Journal of Chinese Ophthalmology
基金
中国中医科学院科技创新工程重大攻关项目(CI2021A02607)。
