摘要
目的:观察膝黄脑府消瘀汤联合超早期软通道微创颅内血肿清除术治疗高血压性脑出血的临床效果。方法:将72例高血压性脑出血患者随机分为观察组和对照组各36例,所有患者均接受超早期软通道微创颅内血肿清除术治疗,对照组术后采用液化剂、抗生素等常规治疗,观察组在对照组基础上口服膝黄脑府消瘀汤治疗,2组疗程均为4周。比较2组治疗前后颅内血肿及周围水肿改善情况,比较2组术后7、14 d时美国国立卫生研究院卒中量表(NIHSS)评分,比较2组治疗期间不良反应发生情况。结果:观察组愈显率为80.56%,对照组为52.78%,2组比较,差异有统计学意义(P<0.05)。2组颅内血肿、周围水肿体积均较治疗前缩小(P<0.05),且观察组颅内血肿、周围水肿体积均小于对照组(P<0.05)。术后7、14 d,观察组NIHSS评分低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应发生率为5.56%,对照组为22.22%,2组比较,差异有统计学意义(P<0.05)。结论:膝黄脑府消瘀汤联合超早期软通道微创颅内血肿清除术治疗高血压性脑出血,能显著减轻颅内血肿及周围水肿情况,促进患者神经功能康复,且不良反应发生率较低。
Objective:To observe the clinical effect of the therapy of Xihuang Naofu Xiaoyu Decoction combined with super-early soft channel minimally invasive intracranial hematoma evacuation on hypertensive cerebral hemorrhage.Methods:A total of 72 patients with hypertensive cerebral hemorrhage were randomly divided into the observation group and the control group,with 36 cases in each group.All patients were treated with super-early soft channel minimally invasive intracranial hematoma evacuation.The control group was treated with routine treatment such as liquefier and antibiotics after operation,the observation group was additionally treated with Xihuang Naofu Xiaoyu Decoction based on the treatment of the control group.Both groups were treated for four weeks.Before and after treatment,the improvement of intracranial hematoma and perilesional edema were compared between the two groups.The scores of National Institutes of Health Stroke Scale(NIHSS)in 7 and 14 days after operation were compared between the two groups.The incidence of adverse reactions during treatment was compared between the two groups.Results:The effective rate was 80.56%in the observation group and 52.78%in the control group,and the difference between the two groups was significant(P<0.05).After treatment,the volumes of intracranial hematoma and perilesional edema in the two groups were reduced when compared with those before treatment(P<0.05),and the above two volumes in the observation group were smaller than those in the control group(P<0.05).The score of NIHSS in the observation group were lower than that in the control group 7 and 14 days after operation,differences being significant(P<0.05).The incidence of adverse reactions was 5.56%in the observation group and 22.22%in the control group,the difference being significant(P<0.05).Conclusion:The therapy of Xihuang Naofu Xiaoyu Decoction combined with super-early soft channel minimally invasive intracranial hematoma evacuation for hypertensive cerebral hemorrhage can significantly reduce the intracr
作者
郭立岭
王静
原茁森
GUO Liling;WANG Jing;YUAN Zhuosen
出处
《新中医》
CAS
2023年第12期26-29,共4页
New Chinese Medicine
关键词
高血压性脑出血
超早期软通道微创颅内血肿清除术
膝黄脑府消瘀汤
美国国立卫生研究院卒中量表
Hypertensive cerebral hemorrhage
Super-early soft channel minimally invasive intracranial hematoma evacuation
Xihuang Naofu Xiaoyu Decoction
National Institutes of Health Stroke Scale
