摘要
目的 分析复方聚乙二醇电解质、利那洛肽联合应用对功能性便秘患者肠镜检查前肠道准备中的效果。方法 选取2020年10月至2021年10月浙江省台州市第一人民医院接受肠镜检查的功能性便秘患者155例,根据随机数字表法将其分为对照组(77例)、研究组(78例),对照组采用复方聚乙二醇电解质进行肠道准备,研究组采用复方聚乙二醇电解质联合利那洛肽进行肠道准备。比较两组检查前2 d及检查后1 d的胃肠道症状分级评分量表评分、肠鸣音时间、肛门排气时间,记录两组肠道清洁度、患者主观耐受程度及不良反应。结果 检查后1 d,两组胃肠道症状分级评分量表评分低于检查前2 d,且研究组低于对照组(P<0.05)。检查后1 d,两组肠鸣音时间、肛门排气时间短于检查前2 d,且研究组短于对照组(P<0.05)。研究组患者主观耐受程度及肠道清洁度优于对照组(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论 采用复方聚乙二醇电解质联合利那洛肽方案进行肠镜检查前肠道准备,患者肠蠕动功能得到了有效改善,且肠道清洁能力显著增加,达到了提高患者主观耐受程度的效果。
Objective To analyze the effect of combined application of compound polyethylene glycol electrolyte and Linalotide on bowel preparation before colonoscopy in patients with functional constipation.Methods A total of 155 patients with functional constipation underwent colonoscopy in Taizhou First People’s Hospital of Zhejiang Province from October 2020 to October 2021 were selected and divided into control group(77 cases)and study group(78 cases)according to random number table method.The control group used compound polyethylene glycol electrolyte for intestinal preparation.The study group used compound polyethylene glycol electrolyte combined with Linalotide for intestinal preparation.Gastrointestinal symptom grading scale scores,bowel sound time,and anal exhaust time of the two groups were compared two days before examination and one day after examination,and intestinal cleanliness,subjective tolerance,and adverse reactions of the two groups were recorded.Results After one day of examination,the scores of gastrointestinal symptom rating scale in both groups were lower than those at two days before examination,and those in the study group were lower than those in the control group(P<0.05).After one day of examination,the bowel sound time and anal exhaust time of the two groups were shorter than those at two days before examination,and those in the study group were shorter than those in the control group(P<0.05).The subjective tolerance and intestinal cleanliness of the study group were better than those of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of compound polyethylene glycol electrolyte and Linalotide for intestinal preparation before colonoscopy effectively improve the peristaltic function of the patients,and significantly increase the intestinal cleaning ability,achieve the effect of improving the degree of subjective tolerance of patients.
作者
吴振兴
林颖
WU Zhenxing;LIN Ying(Department of Gastroenterology,Taizhou First People’s Hospital,Zhejiang Province,Taizhou318020,China)
出处
《中国医药导报》
CAS
2023年第19期108-111,共4页
China Medical Herald
基金
浙江省台州市科技计划项目(22ywa30)。
关键词
复方聚乙二醇电解质
利那洛肽
功能性便秘
肠镜检查
肠道准备
Compound polyethylene glycol electrolyte
Linaloptide
Functional constipation
Colonoscopy
Bowel preparation
