摘要
前哨淋巴结(SLN)是原发肿瘤淋巴结转移必经的首站淋巴结,各类示踪剂是目前SLN领域的研究热点。国产纳米炭混悬液(CNP)作为第三代特异性淋巴示踪剂,具有良好的淋巴系统趋向性,能在短时间内对淋巴结进行染色且不进入血液循环,在各类恶性肿瘤中得到了广泛应用。虽然仍有不少因素会影响到CNP示踪的有效性,但与其余种类示踪剂相比具有安全高效、无放射性、操作简便等优势,有望成为识别恶性肿瘤SLN转移的有力手段。
Sentinel lymph nodes(SLNs)are the first lymph nodes to undergo lymph node metastasis from primary tumors,and various tracers are currently being researched in the field of SLNs.Domestic carbon nanoparticles suspension(CNP)has a good lymphatic system tropism,can indeed stain lymph nodes in a short time without entering the blood circulation,and has been widely used in various malignant tumors as a third generation specific lymphatic tracer.Although there are still many factors that affect the effectiveness of CNP tracer,CNP has the advantages of safety,high efficiency,non-radioactivity and easy operation compared with other kinds of tracers,and is expected to be a powerful means to identify SLNs metastasis of malignant tumors.
作者
王熠昕
曹蒙
王焱
Wang Yixin;Cao Meng;Wang Yan(Department of Dermatological Surgery,Hospital for Skin Diseases,Institute of Dermatology,Chinese Academy of Medical Science,Peking Union Medical College,Nanjing 210042,China;Department of Cosmetic Laser Surgery,Hospital for Skin Diseases,Institute of Dermatology,Chinese Academy of Medical Science,Peking Union Medical College,Nanjing 210042,China)
出处
《国际肿瘤学杂志》
CAS
2023年第1期22-27,共6页
Journal of International Oncology
基金
国家自然科学基金(81872216)。
关键词
肿瘤
淋巴结
纳米粒子
Neoplasms
Lymph node
Nanoparticles
