摘要
目的探讨妊娠晚期室性早搏的发生状况和危险因素及其对母婴结局的影响。方法选取2019年10月至2022年10月于新余市妇幼保健院孕检的80例孕妇作为研究对象,均行十二导联心电图检查,依据是否伴有室性早搏分为正常妊娠组及合并室性早搏组,收集两组年龄、体重、分娩情况、文化程度、高脂血症、妊娠高血压、妊娠糖尿病、合并原发心脏疾病、焦虑、抑郁等多方面基础资料,先开展单因素分析,将有统计学差异的项目行logistic回归分析,获得影响妊娠晚期室性早搏发生的独立危险因素;并比较两组母婴结局情况。结果80例妊娠晚期孕妇共检出28例伴有室性早搏,发生率为35.00%(28/80)。单因素分析结果显示,两组的年龄、体重、高脂血症、妊娠高血压、妊娠糖尿病、合并原发心脏疾病、焦虑、抑郁占比比较,差异有统计学意义(P<0.05)。多因素logistic分析结果显示,年龄≥35岁(β=2.920,OR=18.545,95%CI:5.203~66.107)、体重≥75 kg(β=1.310,OR=3.706,95%CI:1.410~9.738)、高脂血症(β=1.870,OR=6.491,95%CI:2.329~18.092)、妊娠高血压(β=1.852,OR=6.370,95%CI:2.257~17.978)、妊娠糖尿病(β=1.848,OR=6.346,95%CI:2.203~18.278)、合并原发心脏疾病(β=2.197,OR=9.000,95%CI:2.540~31.893)、焦虑(β=1.746,OR=5.730,95%CI:2.103~15.611)、抑郁(β=1.819,OR=6.167,95%CI:2.233~17.032)为影响妊娠晚期室性早搏发生的高危因素(P<0.05)。合并室性早搏组的不良母婴结局总发生率高于正常妊娠组,差异有统计学意义(P<0.05)。结论妊娠晚期室性早搏发生率偏高,与年龄≥35岁、体重≥75 kg、高脂血症、妊娠高血压、妊娠糖尿病、合并原发心脏疾病、焦虑、抑郁关系密切,且室性早搏可增加不良母婴结局风险,还需及早开展针对性防治。
Objective To investigate the occurrence and risk factors of ventricular premature beats(VPB)in the third trimester of pregnancy and its influence on the maternal and infant outcomes.Methods Eighty pregnant women who underwent pregnancy examination in Xinyu Maternal and Child Health Hospital from October 2019 to October 2022 were selected as the study subjects.All of them underwent 12 lead ECG examination.They were divided into normal pregnancy group and combined with VPB group according to whether they were accompanied with VPB.Basic data such as age,body weight,delivery status,education level,hyperlipidemia,gestational hypertension,gestational diabetes,combined with primary heart disease,anxiety and depression were collected in the two groups.Univariate analysis was carried out first,and logistic regression analysis was performed for items with statistical differences to obtain independent risk factors affecting the occurrence of VPB in the third trimester.The outcomes of the two groups were compared.Results A total of 28 cases of premature ventricular beat were detected in 80 pregnant women in the third trimester,the incidence was 35.00%(28/80).The results of univariate analysis showed that there were statistically significant differences in age,body weight,hyperlipidemia,gestational hypertension,gestational diabetes,combined primary heart disease,anxiety and depression between the two groups(P<0.05).Multivariate logistic analysis showed that age≥35 years old(β=2.920,OR=18.545,95%CI:5.203-66.107),body weight≥75 kg(β=1.310,OR=3.706,95%CI:1.410-9.738),hyperlipidemia(β=1.870,OR=6.491,95%CI:2.329-18.092),gestational hypertension(β=1.852,OR=6.370,95%CI:2.257-17.978),gestational diabetes mellitus(β=1.848,OR=6.346,95%CI:2.203-18.278),combined with primary heart disease(β=2.197,OR=9.000,95%CI:2.540-31.893),anxiety(β=1.746,OR=5.730,95%CI:2.103-15.611),depression(β=1.819,OR=6.167,95%CI:2.233-17.032)were the high risk factors for the occurrence of VPB in the third trimester of pregnancy(P<0.05).The total incid
作者
杨文思
YANG Wensi(Electrocardiogram Room,Xinyu Maternal and Child Health Hospital,Jiangxi Province,Xinyu 336000,China)
出处
《中国当代医药》
CAS
2023年第21期63-66,共4页
China Modern Medicine
基金
江西省新余市社会发展指导性科技计划项目(20213090936)。
关键词
妊娠晚期
室性早搏
危险因素
母婴结局
The third trimester of pregnancy
Ventricular premature beat
Risk factors
Maternal and infant outcomes